Jackson KD - Search Results

1

Advances and Challenges in Modeling Cannabidiol Pharmacokinetics and Hepatotoxicity.

Beers JL, Zhou Z, Jackson KD. Beers JL, et al. Among authors: jackson kd. Drug Metab Dispos. 2024 May 16;52(6):508-515. doi: 10.1124/dmd.123.001435. Drug Metab Dispos. 2024. PMID: 38286636 Review.

2

Interindividual Variation in CYP3A Activity Influences Lapatinib Bioactivation.

Bissada JE, Truong V, Abouda AA, Wines KJ, Crouch RD, Jackson KD. Bissada JE, et al. Among authors: jackson kd. Drug Metab Dispos. 2019 Nov;47(11):1257-1269. doi: 10.1124/dmd.119.088823. Epub 2019 Sep 6. Drug Metab Dispos. 2019. PMID: 31492693 Free PMC article.

3

Detoxication versus Bioactivation Pathways of Lapatinib In Vitro: UGT1A1 Catalyzes the Hepatic Glucuronidation of Debenzylated Lapatinib.

Nardone-White DT, Bissada JE, Abouda AA, Jackson KD. Nardone-White DT, et al. Among authors: jackson kd. Drug Metab Dispos. 2021 Mar;49(3):233-244. doi: 10.1124/dmd.120.000236. Epub 2020 Dec 29. Drug Metab Dispos. 2021. PMID: 33376146 Free PMC article.

4

Case Study 11: Considerations for Enzyme Mapping Experiments-Interaction Between the Aldehyde Oxidase Inhibitor Hydralazine and Glutathione.

Crouch RD, Beers JL, Jackson KD. Crouch RD, et al. Among authors: jackson kd. Methods Mol Biol. 2021;2342:809-823. doi: 10.1007/978-1-0716-1554-6_30. Methods Mol Biol. 2021. PMID: 34272718 Free PMC article.

5

Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol.

Beers JL, Fu D, Jackson KD. Beers JL, et al. Among authors: jackson kd. Drug Metab Dispos. 2021 Oct;49(10):882-891. doi: 10.1124/dmd.120.000350. Epub 2021 Jul 30. Drug Metab Dispos. 2021. PMID: 34330718 Free PMC article.

6

Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation.

Burnham EA, Abouda AA, Bissada JE, Nardone-White DT, Beers JL, Lee J, Vergne MJ, Jackson KD. Burnham EA, et al. Among authors: jackson kd. Chem Res Toxicol. 2022 May 16;35(5):792-806. doi: 10.1021/acs.chemrestox.1c00426. Epub 2022 Apr 28. Chem Res Toxicol. 2022. PMID: 35484684 Free PMC article.

7

Vaping additives cannabinoid oil and vitamin E acetate adhere to and damage the human airway epithelium.

Reidel B, Abdelwahab S, Wrennall JA, Clapp PW, Beers JL, Jackson KD, Tarran R, Kesimer M. Reidel B, et al. Among authors: jackson kd. J Appl Toxicol. 2023 May;43(5):680-693. doi: 10.1002/jat.4415. Epub 2022 Nov 30. J Appl Toxicol. 2023. PMID: 36372912 Free PMC article.

8

Verifying in vitro-determined enzyme contributions to cannabidiol clearance for exposure predictions in human through physiologically-based pharmacokinetic modeling.

Yeung CHT, Beers JL, Jackson KD, Edginton AN. Yeung CHT, et al. Among authors: jackson kd. CPT Pharmacometrics Syst Pharmacol. 2023 Mar;12(3):320-332. doi: 10.1002/psp4.12908. Epub 2023 Jan 8. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36540909 Free PMC article.

9

Cytosolic Enzymes Generate Cannabinoid Metabolites 7-Carboxycannabidiol and 11-Nor-9-carboxytetrahydrocannabinol.

Beers JL, Authement AK, Isoherranen N, Jackson KD. Beers JL, et al. Among authors: jackson kd. ACS Med Chem Lett. 2023 Apr 20;14(5):614-620. doi: 10.1021/acsmedchemlett.3c00017. eCollection 2023 May 11. ACS Med Chem Lett. 2023. PMID: 37197460 Free PMC article.

10

Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine.

Jackson KD, Achour B, Lee J, Geffert RM, Beers JL, Latham BD. Jackson KD, et al. Drug Metab Dispos. 2023 Oct;51(10):1238-1253. doi: 10.1124/dmd.122.001066. Epub 2023 Jul 7. Drug Metab Dispos. 2023. PMID: 37419681 Free PMC article. Review.

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