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Safety and Pharmacokinetics of Quizartinib Combination Therapy With Standard Induction and Consolidation Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemia: Results from Two Phase 1 Trials in Japan and China.
Qi J, Choi I, Ota S, Ichikawa S, Fujishima N, Iida H, Sugiura I, Sugiura K, Murata Y, Inoue H, Ohwada S, Wang J. Qi J, et al. Among authors: ota s. Clin Pharmacol Drug Dev. 2024 May;13(5):560-571. doi: 10.1002/cpdd.1353. Epub 2024 Jan 29. Clin Pharmacol Drug Dev. 2024. PMID: 38284515 Clinical Trial.
Development and evaluation of a rapid one-step high sensitivity real-time quantitative PCR system for minor BCR-ABL (e1a2) test in Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL).
Hidaka M, Inokuchi K, Uoshima N, Takahashi N, Yoshida N, Ota S, Nakamae H, Iwasaki H, Watanabe K, Kosaka Y, Komatsu N, Meguro K, Najima Y, Eto T, Kondo T, Kimura S, Yoshida C, Ishikawa Y, Sawa M, Hata T, Horibe K, Iida H, Shimomura T, Dobashi N, Sugiura I, Makiyama J, Miyagawa N, Sato A, Ito R, Matsumura I, Kanakura Y, Naoe T. Hidaka M, et al. Among authors: ota s. Jpn J Clin Oncol. 2024 Feb 7;54(2):153-159. doi: 10.1093/jjco/hyad156. Jpn J Clin Oncol. 2024. PMID: 37986553 Free PMC article.
A phase 1/2 study of NS-87/CPX-351 (cytarabine and daunorubicin liposome) in Japanese patients with high-risk acute myeloid leukemia.
Usuki K, Miyamoto T, Yamauchi T, Ando K, Ogawa Y, Onozawa M, Yamauchi T, Kiyoi H, Yokota A, Ikezoe T, Katsuoka Y, Takada S, Aotsuka N, Morita Y, Ishikawa T, Asada N, Ota S, Dohi A, Morimoto K, Imai S, Kishimoto U, Akashi K, Miyazaki Y; Study Group for NS-87/CPX-351. Usuki K, et al. Among authors: ota s. Int J Hematol. 2024 Jun;119(6):647-659. doi: 10.1007/s12185-024-03733-z. Epub 2024 Mar 26. Int J Hematol. 2024. PMID: 38532078 Free PMC article. Clinical Trial.
Real-world effectiveness and safety of ibrutinib in patients with chronic lymphocytic leukemia in Japan: the Orbit study.
Muta T, Masamoto Y, Yamamoto G, Kurahashi S, Kameoka Y, Ota S, Matsuki E, Ozeki K, Toyama T, Takahashi N, Kumode T, Aotsuka N, Yoshimura T, Tamura H, Omi A, Shibayama K, Watanabe A, Isobe Y, Kojima K, Takizawa J, Nagai H, Suzumiya J, Aoki S. Muta T, et al. Among authors: ota s. Int J Hematol. 2024 Nov 26. doi: 10.1007/s12185-024-03875-0. Online ahead of print. Int J Hematol. 2024. PMID: 39586984
FLT3 inhibitors and hematopoietic cell transplantation prolong survival in patients with FLT3-ITD-positive AML.
Matsukawa T, Onozawa M, Kondo T, Kanaya M, Hidaka D, Ota S, Mori A, Shigematsu A, Miyagishima T, Kakinoki Y, Hashiguchi J, Yamamoto S, Yamamoto M, Wakasa K, Takahata M, Ishihara T, Haseyama Y, Fujimi A, Igarashi T, Sarashina T, Iyama S, Kobayashi R, Sakai H, Fujimoto K, Inamura J, Kanisawa Y, Hirabayashi S, Endo T, Hashimoto D, Teshima T. Matsukawa T, et al. Among authors: ota s. Ann Hematol. 2024 Dec;103(12):5333-5340. doi: 10.1007/s00277-024-06125-9. Epub 2024 Nov 30. Ann Hematol. 2024. PMID: 39614924
Machine learning evaluation of intensified conditioning on haematopoietic stem cell transplantation in adult acute lymphoblastic leukemia patients.
Jo T, Inoue K, Ueda T, Iwasaki M, Akahoshi Y, Nishiwaki S, Hatsusawa H, Nishida T, Uchida N, Ito A, Tanaka M, Takada S, Kawakita T, Ota S, Katayama Y, Takahashi S, Onizuka M, Hasegawa Y, Kataoka K, Kanda Y, Fukuda T, Tabuchi K, Atsuta Y, Arai Y. Jo T, et al. Among authors: ota s. Commun Med (Lond). 2024 Nov 25;4(1):247. doi: 10.1038/s43856-024-00680-y. Commun Med (Lond). 2024. PMID: 39587218 Free PMC article.
Outcomes of transplant-eligible patients with myelodysplastic syndrome with excess blasts registered in an observational study: The JALSG-CS11-MDS-SCT.
Nakagawa N, Ishiyama K, Usuki K, Takada S, Tomikawa T, Handa H, Katsuoka Y, Hirano D, Sezaki N, Sumi M, Fujisawa S, Taniguchi Y, Mugitani A, Yoshimura T, Ohtsuka E, Takase K, Suehiro Y, Ota S, Kajiguchi T, Maeda T, Yamamoto M, Ohtake S, Katsumi A, Kiyoi H, Matsumura I, Miyazaki Y. Nakagawa N, et al. Among authors: ota s. Ann Hematol. 2024 Jan;103(1):307-320. doi: 10.1007/s00277-023-05527-5. Epub 2023 Nov 8. Ann Hematol. 2024. PMID: 37940714
Myeloablative conditioning in cord blood transplantation for acute myeloid leukemia patients is efficacious only until age 55.
Oshima S, Arai Y, Kondo T, Yano S, Hirabayashi S, Uchida N, Onizuka M, Miyakoshi S, Tanaka M, Takahashi S, Hayashi M, Kawakita T, Uehara Y, Ota S, Izumi T, Sawa M, Nishida T, Katayama Y, Nagafuji K, Kato K, Ichinohe T, Atsuta Y, Yanada M. Oshima S, et al. Among authors: ota s. Bone Marrow Transplant. 2025 Jan 21. doi: 10.1038/s41409-025-02508-2. Online ahead of print. Bone Marrow Transplant. 2025. PMID: 39838078
1,644 results