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GWAS-identified hyperuricemia-associated IGF1R variant rs6598541 has a limited role in urate mediated inflammation in human mononuclear cells.
Gaal OI, Liu R, Marginean D, Badii M, Cabău G, Hotea I, Nica V, Colcear D; HINT Consortium; Pamfil C, Merriman TR, Rednic S, Popp RA, Crișan TO, Joosten LAB. Gaal OI, et al. Among authors: colcear d. Sci Rep. 2024 Feb 12;14(1):3565. doi: 10.1038/s41598-024-53209-7. Sci Rep. 2024. PMID: 38347000 Free PMC article.
Downregulation of type I interferon signalling pathway by urate in primary human PBMCs.
Badii M, Nica V, Straton AR, Kischkel B, Gaal O, Cabău G, Klück V, Hotea I; HINT Consortium; Novakovic B, Pamfil C, Rednic S, Netea MG, Popp RA, Joosten LAB, Crișan TO. Badii M, et al. Immunology. 2025 Jan;174(1):100-112. doi: 10.1111/imm.13858. Epub 2024 Oct 1. Immunology. 2025. PMID: 39354748 Free PMC article.
Maternal/newborn genotype contribution of the renin-angiotensin system (Met235Thr, Thr174Met, I/D-ACE, A2350G-ACE, A1166C-AT2R1, C3123A- AT2R2, 83A/G-REN) to the risk of pre-eclampsia: a Romanian study.
Procopciuc LM, Caracostea G, Zaharie G, Puscas M, Iordache G, Popa M, Colcear D, Olteanu I, Stamatian F. Procopciuc LM, et al. Among authors: colcear d. J Renin Angiotensin Aldosterone Syst. 2011 Dec;12(4):539-48. doi: 10.1177/1470320311399603. Epub 2011 Mar 24. J Renin Angiotensin Aldosterone Syst. 2011. PMID: 21436209 Free article.