Beckedorff F - Search Results

1

Ecto-CD38-NADase inhibition modulates cardiac metabolism and protects mice against doxorubicin-induced cardiotoxicity.

Peclat TR, Agorrody G, Colman L, Kashyap S, Zeidler JD, Chini CCS, Warner GM, Thompson KL, Dalvi P, Beckedorff F, Ebtehaj S, Herrmann J, van Schooten W, Chini EN. Peclat TR, et al. Among authors: beckedorff f. Cardiovasc Res. 2024 Mar 14;120(3):286-300. doi: 10.1093/cvr/cvae025. Cardiovasc Res. 2024. PMID: 38271281

2

Protein Kinase D-Dependent Downregulation of Immediate Early Genes through Class IIA Histone Deacetylases in Acute Lymphoblastic Leukemia.

Sun G, Shvab A, Leclerc GJ, Li B, Beckedorff F, Shiekhattar R, Barredo JC. Sun G, et al. Among authors: beckedorff f. Mol Cancer Res. 2021 Aug;19(8):1296-1307. doi: 10.1158/1541-7786.MCR-20-0808. Epub 2021 May 12. Mol Cancer Res. 2021. PMID: 33980612 Free article.

3

Integrator orchestrates RAS/ERK1/2 signaling transcriptional programs.

Yue J, Lai F, Beckedorff F, Zhang A, Pastori C, Shiekhattar R. Yue J, et al. Among authors: beckedorff f. Genes Dev. 2017 Sep 1;31(17):1809-1820. doi: 10.1101/gad.301697.117. Genes Dev. 2017. PMID: 28982763 Free PMC article.

4

Targeted chemotherapy overcomes drug resistance in melanoma.

Yue J, Vendramin R, Liu F, Lopez O, Valencia MG, Gomes Dos Santos H, Gaidosh G, Beckedorff F, Blumenthal E, Speroni L, Nimer SD, Marine JC, Shiekhattar R. Yue J, et al. Among authors: beckedorff f. Genes Dev. 2020 May 1;34(9-10):637-649. doi: 10.1101/gad.333864.119. Epub 2020 Apr 2. Genes Dev. 2020. PMID: 32241802 Free PMC article.

5

The Integrator complex regulates microRNA abundance through RISC loading.

Kirstein N, Dokaneheifard S, Cingaram PR, Valencia MG, Beckedorff F, Gomes Dos Santos H, Blumenthal E, Tayari MM, Gaidosh GS, Shiekhattar R. Kirstein N, et al. Among authors: beckedorff f. Sci Adv. 2023 Feb 10;9(6):eadf0597. doi: 10.1126/sciadv.adf0597. Epub 2023 Feb 10. Sci Adv. 2023. PMID: 36763664 Free PMC article.

6

Integrator enforces the fidelity of transcriptional termination at protein-coding genes.

Dasilva LF, Blumenthal E, Beckedorff F, Cingaram PR, Gomes Dos Santos H, Edupuganti RR, Zhang A, Dokaneheifard S, Aoi Y, Yue J, Kirstein N, Tayari MM, Shilatifard A, Shiekhattar R. Dasilva LF, et al. Among authors: beckedorff f. Sci Adv. 2021 Nov 5;7(45):eabe3393. doi: 10.1126/sciadv.abe3393. Epub 2021 Nov 3. Sci Adv. 2021. PMID: 34730992 Free PMC article.

7

The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts.

Beckedorff F, Blumenthal E, daSilva LF, Aoi Y, Cingaram PR, Yue J, Zhang A, Dokaneheifard S, Valencia MG, Gaidosh G, Shilatifard A, Shiekhattar R. Beckedorff F, et al. Cell Rep. 2020 Jul 21;32(3):107917. doi: 10.1016/j.celrep.2020.107917. Cell Rep. 2020. PMID: 32697989 Free PMC article.

8

Single-nucleus RNA sequencing of developing superior colliculus identifies neuronal diversity and candidate mediators of circuit assembly.

Choi JS, Ayupe AC, Beckedorff F, Catanuto P, McCartan R, Levay K, Park KK. Choi JS, et al. Among authors: beckedorff f. Cell Rep. 2023 Sep 26;42(9):113037. doi: 10.1016/j.celrep.2023.113037. Epub 2023 Aug 24. Cell Rep. 2023. PMID: 37624694 Free PMC article.

9

Identification of long noncoding RNAs in injury-resilient and injury-susceptible mouse retinal ganglion cells.

Ayupe AC, Beckedorff F, Levay K, Yon B, Salgueiro Y, Shiekhattar R, Park KK. Ayupe AC, et al. Among authors: beckedorff f. BMC Genomics. 2021 Oct 14;22(1):741. doi: 10.1186/s12864-021-08050-x. BMC Genomics. 2021. PMID: 34649511 Free PMC article.

10

Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms.

Chan HL, Beckedorff F, Zhang Y, Garcia-Huidobro J, Jiang H, Colaprico A, Bilbao D, Figueroa ME, LaCava J, Shiekhattar R, Morey L. Chan HL, et al. Among authors: beckedorff f. Nat Commun. 2018 Aug 23;9(1):3377. doi: 10.1038/s41467-018-05728-x. Nat Commun. 2018. PMID: 30139998 Free PMC article.

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