Sierecki E - Search Results

1

The HIV capsid mimics karyopherin engagement of FG-nucleoporins.

Dickson CF, Hertel S, Tuckwell AJ, Li N, Ruan J, Al-Izzi SC, Ariotti N, Sierecki E, Gambin Y, Morris RG, Towers GJ, Böcking T, Jacques DA. Dickson CF, et al. Among authors: sierecki e. Nature. 2024 Feb;626(8000):836-842. doi: 10.1038/s41586-023-06969-7. Epub 2024 Jan 24. Nature. 2024. PMID: 38267582 Free PMC article.

2

Biochemical characterization of the phosphatase domain of the tumor suppressor PH domain leucine-rich repeat protein phosphatase.

Sierecki E, Newton AC. Sierecki E, et al. Biochemistry. 2014 Jun 24;53(24):3971-81. doi: 10.1021/bi500428j. Epub 2014 Jun 12. Biochemistry. 2014. PMID: 24892992 Free PMC article.

3

PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms.

Brognard J, Sierecki E, Gao T, Newton AC. Brognard J, et al. Among authors: sierecki e. Mol Cell. 2007 Mar 23;25(6):917-31. doi: 10.1016/j.molcel.2007.02.017. Mol Cell. 2007. PMID: 17386267 Free article.

4

Discovery of small molecule inhibitors of the PH domain leucine-rich repeat protein phosphatase (PHLPP) by chemical and virtual screening.

Sierecki E, Sinko W, McCammon JA, Newton AC. Sierecki E, et al. J Med Chem. 2010 Oct 14;53(19):6899-911. doi: 10.1021/jm100331d. J Med Chem. 2010. PMID: 20836557 Free PMC article.

5

Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens.

Han SP, Gambin Y, Gomez GA, Verma S, Giles N, Michael M, Wu SK, Guo Z, Johnston W, Sierecki E, Parton RG, Alexandrov K, Yap AS. Han SP, et al. Among authors: sierecki e. J Biol Chem. 2014 Mar 14;289(11):7764-75. doi: 10.1074/jbc.M113.544478. Epub 2014 Jan 27. J Biol Chem. 2014. PMID: 24469447 Free PMC article.

6

Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae.

Gambin Y, Ariotti N, McMahon KA, Bastiani M, Sierecki E, Kovtun O, Polinkovsky ME, Magenau A, Jung W, Okano S, Zhou Y, Leneva N, Mureev S, Johnston W, Gaus K, Hancock JF, Collins BM, Alexandrov K, Parton RG. Gambin Y, et al. Among authors: sierecki e. Elife. 2013 Jan 1;3:e01434. doi: 10.7554/eLife.01434. Elife. 2013. PMID: 24473072 Free PMC article.

7

A cell-free approach to accelerate the study of protein-protein interactions in vitro.

Sierecki E, Giles N, Polinkovsky M, Moustaqil M, Alexandrov K, Gambin Y. Sierecki E, et al. Interface Focus. 2013 Oct 6;3(5):20130018. doi: 10.1098/rsfs.2013.0018. Interface Focus. 2013. PMID: 24511386 Free PMC article. Review.

8

Confocal Spectroscopy to Study Dimerization, Oligomerization and Aggregation of Proteins: A Practical Guide.

Gambin Y, Polinkovsky M, Francois B, Giles N, Bhumkar A, Sierecki E. Gambin Y, et al. Among authors: sierecki e. Int J Mol Sci. 2016 Apr 30;17(5):655. doi: 10.3390/ijms17050655. Int J Mol Sci. 2016. PMID: 27144560 Free PMC article. Review.

9

Evaluation of Lipopeptides as Toll-like Receptor 2 Ligands.

Hussein WM, Choi PM, Zhang C, Su M, Sierecki E, Johnston W, Fagan V, Alexandrov K, Skwarczynski M, Gambin Y, Toth I, Simerska P. Hussein WM, et al. Among authors: sierecki e. Curr Drug Deliv. 2017;14(7):935-943. doi: 10.2174/1567201813666160804114107. Curr Drug Deliv. 2017. PMID: 27494158

10

Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation.

Chai YJ, Sierecki E, Tomatis VM, Gormal RS, Giles N, Morrow IC, Xia D, Götz J, Parton RG, Collins BM, Gambin Y, Meunier FA. Chai YJ, et al. Among authors: sierecki e. J Cell Biol. 2016 Sep 12;214(6):705-18. doi: 10.1083/jcb.201512016. Epub 2016 Sep 5. J Cell Biol. 2016. PMID: 27597756 Free PMC article.

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