Blackman MJ - Search Results

1

Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets.

Bennett JM, Narwal SK, Kabeche S, Abegg D, Hackett F, Yeo T, Li VL, Muir RK, Faucher FF, Lovell S, Blackman MJ, Adibekian A, Yeh E, Fidock DA, Bogyo M. Bennett JM, et al. Among authors: blackman mj. bioRxiv [Preprint]. 2024 Jan 11:2024.01.11.575224. doi: 10.1101/2024.01.11.575224. bioRxiv. 2024. Update in: Cell Chem Biol. 2024 Sep 19;31(9):1714-1728.e10. doi: 10.1016/j.chembiol.2024.07.006 PMID: 38260474 Free PMC article. Updated. Preprint.

2

Functional characterization of the propeptide of Plasmodium falciparum subtilisin-like protease-1.

Jean L, Hackett F, Martin SR, Blackman MJ. Jean L, et al. Among authors: blackman mj. J Biol Chem. 2003 Aug 1;278(31):28572-9. doi: 10.1074/jbc.M303827200. Epub 2003 May 22. J Biol Chem. 2003. PMID: 12764150 Free article.

3

Unique insertions within Plasmodium falciparum subtilisin-like protease-1 are crucial for enzyme maturation and activity.

Jean L, Withers-Martinez C, Hackett F, Blackman MJ. Jean L, et al. Among authors: blackman mj. Mol Biochem Parasitol. 2005 Dec;144(2):187-97. doi: 10.1016/j.molbiopara.2005.07.008. Epub 2005 Sep 8. Mol Biochem Parasitol. 2005. PMID: 16183148

4

Subtilisin-like Serine Protease 1 (SUB1) as an Emerging Antimalarial Drug Target: Current Achievements in Inhibitor Discovery.

Lidumniece E, Withers-Martinez C, Hackett F, Blackman MJ, Jirgensons A. Lidumniece E, et al. Among authors: blackman mj. J Med Chem. 2022 Oct 13;65(19):12535-12545. doi: 10.1021/acs.jmedchem.2c01093. Epub 2022 Sep 22. J Med Chem. 2022. PMID: 36137276 Review.

5

Peptidic Boronic Acid Plasmodium falciparum SUB1 Inhibitors with Improved Selectivity over Human Proteasome.

Withers-Martinez C, Lidumniece E, Hackett F, Collins CR, Taha Z, Blackman MJ, Jirgensons A. Withers-Martinez C, et al. Among authors: blackman mj. J Med Chem. 2024 Aug 8;67(15):13033-13055. doi: 10.1021/acs.jmedchem.4c01005. Epub 2024 Jul 25. J Med Chem. 2024. PMID: 39051854 Free PMC article.

6

PfSUB-2: a second subtilisin-like protein in Plasmodium falciparum merozoites.

Hackett F, Sajid M, Withers-Martinez C, Grainger M, Blackman MJ. Hackett F, et al. Among authors: blackman mj. Mol Biochem Parasitol. 1999 Oct 15;103(2):183-95. doi: 10.1016/s0166-6851(99)00122-x. Mol Biochem Parasitol. 1999. PMID: 10551362

7

Expression of recombinant Plasmodium falciparum subtilisin-like protease-1 in insect cells. Characterization, comparison with the parasite protease, and homology modeling.

Withers-Martinez C, Saldanha JW, Ely B, Hackett F, O'Connor T, Blackman MJ. Withers-Martinez C, et al. Among authors: blackman mj. J Biol Chem. 2002 Aug 16;277(33):29698-709. doi: 10.1074/jbc.M203088200. Epub 2002 Jun 6. J Biol Chem. 2002. PMID: 12052828 Free article.

8

Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite.

O'Donnell RA, Hackett F, Howell SA, Treeck M, Struck N, Krnajski Z, Withers-Martinez C, Gilberger TW, Blackman MJ. O'Donnell RA, et al. Among authors: blackman mj. J Cell Biol. 2006 Sep 25;174(7):1023-33. doi: 10.1083/jcb.200604136. J Cell Biol. 2006. PMID: 17000879 Free PMC article.

9

Malarial EBA-175 region VI crystallographic structure reveals a KIX-like binding interface.

Withers-Martinez C, Haire LF, Hackett F, Walker PA, Howell SA, Smerdon SJ, Dodson GG, Blackman MJ. Withers-Martinez C, et al. Among authors: blackman mj. J Mol Biol. 2008 Jan 18;375(3):773-81. doi: 10.1016/j.jmb.2007.10.071. Epub 2007 Nov 1. J Mol Biol. 2008. PMID: 18036613

10

An inhibitory antibody blocks interactions between components of the malarial invasion machinery.

Collins CR, Withers-Martinez C, Hackett F, Blackman MJ. Collins CR, et al. Among authors: blackman mj. PLoS Pathog. 2009 Jan;5(1):e1000273. doi: 10.1371/journal.ppat.1000273. Epub 2009 Jan 23. PLoS Pathog. 2009. PMID: 19165323 Free PMC article.

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