Knollmann BC - Search Results

1

ent-Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2 ^-/- Mice.

Gochman A, Do TQ, Kim K, Schwarz JA, Thorpe MP, Blackwell DJ, Ritschel PA, Smith AN, Rebbeck RT, Akers WS, Cornea RL, Laver DR, Johnston JN, Knollmann BC. Gochman A, et al. Among authors: knollmann bc. Mol Pharmacol. 2024 Feb 15;105(3):194-201. doi: 10.1124/molpharm.123.000752. Mol Pharmacol. 2024. PMID: 38253398

2

Amitriptyline activates cardiac ryanodine channels and causes spontaneous sarcoplasmic reticulum calcium release.

Chopra N, Laver D, Davies SS, Knollmann BC. Chopra N, et al. Among authors: knollmann bc. Mol Pharmacol. 2009 Jan;75(1):183-95. doi: 10.1124/mol.108.051490. Epub 2008 Oct 9. Mol Pharmacol. 2009. PMID: 18845675 Free PMC article.

3

Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans.

Watanabe H, Chopra N, Laver D, Hwang HS, Davies SS, Roach DE, Duff HJ, Roden DM, Wilde AA, Knollmann BC. Watanabe H, et al. Among authors: knollmann bc. Nat Med. 2009 Apr;15(4):380-3. doi: 10.1038/nm.1942. Epub 2009 Mar 29. Nat Med. 2009. PMID: 19330009 Free PMC article.

4

Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass.

Hilliard FA, Steele DS, Laver D, Yang Z, Le Marchand SJ, Chopra N, Piston DW, Huke S, Knollmann BC. Hilliard FA, et al. Among authors: knollmann bc. J Mol Cell Cardiol. 2010 Feb;48(2):293-301. doi: 10.1016/j.yjmcc.2009.10.005. Epub 2009 Oct 14. J Mol Cell Cardiol. 2010. PMID: 19835880 Free PMC article.

5

Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia.

Hwang HS, Hasdemir C, Laver D, Mehra D, Turhan K, Faggioni M, Yin H, Knollmann BC. Hwang HS, et al. Among authors: knollmann bc. Circ Arrhythm Electrophysiol. 2011 Apr;4(2):128-35. doi: 10.1161/CIRCEP.110.959916. Epub 2011 Jan 26. Circ Arrhythm Electrophysiol. 2011. PMID: 21270101 Free PMC article.

6

Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants.

Hwang HS, Nitu FR, Yang Y, Walweel K, Pereira L, Johnson CN, Faggioni M, Chazin WJ, Laver D, George AL Jr, Cornea RL, Bers DM, Knollmann BC. Hwang HS, et al. Among authors: knollmann bc. Circ Res. 2014 Mar 28;114(7):1114-24. doi: 10.1161/CIRCRESAHA.114.303391. Epub 2014 Feb 21. Circ Res. 2014. PMID: 24563457 Free PMC article.

7

Multiple modes of ryanodine receptor 2 inhibition by flecainide.

Mehra D, Imtiaz MS, van Helden DF, Knollmann BC, Laver DR. Mehra D, et al. Among authors: knollmann bc. Mol Pharmacol. 2014 Dec;86(6):696-706. doi: 10.1124/mol.114.094623. Epub 2014 Oct 1. Mol Pharmacol. 2014. PMID: 25274603 Free PMC article.

8

Essential Role of Calmodulin in RyR Inhibition by Dantrolene.

Oo YW, Gomez-Hurtado N, Walweel K, van Helden DF, Imtiaz MS, Knollmann BC, Laver DR. Oo YW, et al. Among authors: knollmann bc. Mol Pharmacol. 2015 Jul;88(1):57-63. doi: 10.1124/mol.115.097691. Epub 2015 Apr 28. Mol Pharmacol. 2015. PMID: 25920678 Free PMC article.

9

Novel CPVT-Associated Calmodulin Mutation in CALM3 (CALM3-A103V) Activates Arrhythmogenic Ca Waves and Sparks.

Gomez-Hurtado N, Boczek NJ, Kryshtal DO, Johnson CN, Sun J, Nitu FR, Cornea RL, Chazin WJ, Calvert ML, Tester DJ, Ackerman MJ, Knollmann BC. Gomez-Hurtado N, et al. Among authors: knollmann bc. Circ Arrhythm Electrophysiol. 2016 Aug;9(8):10.1161/CIRCEP.116.004161 e004161. doi: 10.1161/CIRCEP.116.004161. Circ Arrhythm Electrophysiol. 2016. PMID: 27516456 Free PMC article.

10

Modelling human calmodulinopathies with induced pluripotent stem cells: progress and challenges.

Gomez-Hurtado N, Blackwell DJ, Knollmann BC. Gomez-Hurtado N, et al. Among authors: knollmann bc. Cardiovasc Res. 2017 Apr 1;113(5):437-439. doi: 10.1093/cvr/cvx041. Cardiovasc Res. 2017. PMID: 28384370 Free PMC article. No abstract available.

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