Brennan L - Search Results

1

Molecular determinants and intracellular targets of taurine signalling in pancreatic islet β-cells.

Turbitt J, Moffett RC, Brennan L, Johnson PRV, Flatt PR, McClenaghan NH, Tarasov AI. Turbitt J, et al. Among authors: brennan l. Acta Physiol (Oxf). 2024 Mar;240(3):e14101. doi: 10.1111/apha.14101. Epub 2024 Jan 20. Acta Physiol (Oxf). 2024. PMID: 38243723

2

A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: metabolism of L-alanine is important to the regulation of insulin secretion.

Brennan L, Shine A, Hewage C, Malthouse JP, Brindle KM, McClenaghan N, Flatt PR, Newsholme P. Brennan L, et al. Diabetes. 2002 Jun;51(6):1714-21. doi: 10.2337/diabetes.51.6.1714. Diabetes. 2002. PMID: 12031957

3

13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and gamma-glutamyl cycle activity in a clonal pancreatic beta-cell line.

Brennan L, Corless M, Hewage C, Malthouse JP, McClenaghan NH, Flatt PR, Newsholme P. Brennan L, et al. Diabetologia. 2003 Nov;46(11):1512-21. doi: 10.1007/s00125-003-1184-7. Epub 2003 Sep 4. Diabetologia. 2003. PMID: 12955201

4

Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion.

Patterson S, Flatt PR, Brennan L, Newsholme P, McClenaghan NH. Patterson S, et al. Among authors: brennan l. J Endocrinol. 2006 May;189(2):301-10. doi: 10.1677/joe.1.06537. J Endocrinol. 2006. PMID: 16648297

5

Investigation of the effects of sulfonylurea exposure on pancreatic beta cell metabolism.

Brennan L, Hewage C, Malthouse JP, McClenaghan NH, Flatt PR, Newsholme P. Brennan L, et al. FEBS J. 2006 Nov;273(22):5160-8. doi: 10.1111/j.1742-4658.2006.05513.x. Epub 2006 Oct 20. FEBS J. 2006. PMID: 17054712 Free article.

6

Prolonged L-alanine exposure induces changes in metabolism, Ca(2+) handling and desensitization of insulin secretion in clonal pancreatic beta-cells.

McClenaghan NH, Scullion SM, Mion B, Hewage C, Malthouse JP, Flatt PR, Newsholme P, Brennan L. McClenaghan NH, et al. Among authors: brennan l. Clin Sci (Lond). 2009 Feb;116(4):341-51. doi: 10.1042/CS20080138. Clin Sci (Lond). 2009. PMID: 18702613

7

NKCC transport mediates the insulinotropic effects of taurine and other small neutral amino acids.

Turbitt J, Brennan L, Moffett RC, Flatt PR, Johnson PRV, Tarasov AI, McClenaghan NH. Turbitt J, et al. Among authors: brennan l. Life Sci. 2023 Mar 1;316:121402. doi: 10.1016/j.lfs.2023.121402. Epub 2023 Jan 18. Life Sci. 2023. PMID: 36669678 Free article.

8

Metabolomic analysis of pancreatic beta cells following exposure to high glucose.

Wallace M, Whelan H, Brennan L. Wallace M, et al. Among authors: brennan l. Biochim Biophys Acta. 2013 Mar;1830(3):2583-90. doi: 10.1016/j.bbagen.2012.10.025. Biochim Biophys Acta. 2013. PMID: 23153904

9

The importance of redox shuttles to pancreatic beta-cell energy metabolism and function.

Bender K, Newsholme P, Brennan L, Maechler P. Bender K, et al. Among authors: brennan l. Biochem Soc Trans. 2006 Nov;34(Pt 5):811-4. doi: 10.1042/BST0340811. Biochem Soc Trans. 2006. PMID: 17052204

10

Uncovering Factors Related to Pancreatic Beta-Cell Function.

Curran AM, Ryan MF, Drummond E, Gibney ER, Gibney MJ, Roche HM, Brennan L. Curran AM, et al. Among authors: brennan l. PLoS One. 2016 Aug 18;11(8):e0161350. doi: 10.1371/journal.pone.0161350. eCollection 2016. PLoS One. 2016. PMID: 27536890 Free PMC article.

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