Eck RJ - Search Results

1

Simple models to understand complex disease: 10 years of progress from Caenorhabditis elegans models of amyotrophic lateral sclerosis and frontotemporal lobar degeneration.

Eck RJ, Stair JG, Kraemer BC, Liachko NF. Eck RJ, et al. Front Neurosci. 2024 Jan 4;17:1300705. doi: 10.3389/fnins.2023.1300705. eCollection 2023. Front Neurosci. 2024. PMID: 38239833 Free PMC article. Review.

2

Regulation of TDP-43 phosphorylation in aging and disease.

Eck RJ, Kraemer BC, Liachko NF. Eck RJ, et al. Geroscience. 2021 Aug;43(4):1605-1614. doi: 10.1007/s11357-021-00383-5. Epub 2021 May 25. Geroscience. 2021. PMID: 34032984 Free PMC article.

3

Pathological tau drives ectopic nuclear speckle scaffold protein SRRM2 accumulation in neuron cytoplasm in Alzheimer's disease.

McMillan PJ, Strovas TJ, Baum M, Mitchell BK, Eck RJ, Hendricks N, Wheeler JM, Latimer CS, Keene CD, Kraemer BC. McMillan PJ, et al. Among authors: eck rj. Acta Neuropathol Commun. 2021 Jun 29;9(1):117. doi: 10.1186/s40478-021-01219-1. Acta Neuropathol Commun. 2021. PMID: 34187600 Free PMC article.

4

SPOP loss of function protects against tauopathy.

Eck RJ, Kow RL, Black AH, Liachko NF, Kraemer BC. Eck RJ, et al. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2207250120. doi: 10.1073/pnas.2207250120. Epub 2022 Dec 27. Proc Natl Acad Sci U S A. 2023. PMID: 36574656 Free PMC article.

5

Transcriptomic evaluation of tau and TDP-43 synergism shows tauopathy predominance and reveals potential modulating targets.

Jadhav VS, Stair JG, Eck RJ, Smukowski SN, Currey HN, Toscano LG, Hincks JC, Latimer CS, Valdmanis PN, Kraemer BC, Liachko NF. Jadhav VS, et al. Among authors: eck rj. Neurobiol Dis. 2024 Apr;193:106441. doi: 10.1016/j.nbd.2024.106441. Epub 2024 Feb 18. Neurobiol Dis. 2024. PMID: 38378122 Free PMC article.

6

[No title available]

[No authors listed] [No authors listed] PMID: 39750990

7

Alternative 3' UTR polyadenylation is disrupted in the rNLS8 mouse model of ALS/FTLD.

Eck RJ, Valdmanis PN, Liachko NF, Kraemer BC. Eck RJ, et al. Mol Brain. 2025 Jan 14;18(1):1. doi: 10.1186/s13041-025-01174-1. Mol Brain. 2025. PMID: 39810199 Free PMC article.

8

To Be or Not To Be…Toxic-Is RNA Association With TDP-43 Complexes Deleterious or Protective in Neurodegeneration?

Loganathan S, Lehmkuhl EM, Eck RJ, Zarnescu DC. Loganathan S, et al. Among authors: eck rj. Front Mol Biosci. 2020 Jan 10;6:154. doi: 10.3389/fmolb.2019.00154. eCollection 2019. Front Mol Biosci. 2020. PMID: 31998750 Free PMC article. Review.

9

External Validation of Mortality Prediction Models for Critical Illness Reveals Preserved Discrimination but Poor Calibration.

Cox EGM, Wiersema R, Eck RJ, Kaufmann T, Granholm A, Vaara ST, Møller MH, van Bussel BCT, Snieder H, Pleijhuis RG, van der Horst ICC, Keus F. Cox EGM, et al. Among authors: eck rj. Crit Care Med. 2023 Jan 1;51(1):80-90. doi: 10.1097/CCM.0000000000005712. Epub 2022 Nov 15. Crit Care Med. 2023. PMID: 36378565

10

Trough anti-Xa activity after intermediate dose nadroparin for thrombosis prophylaxis in critically ill patients with COVID-19 and acute kidney injury.

Eck RJ, van de Leur JJCM, Wiersema R, Cox EGM, Bult W, Spanjersberg AJ, van der Horst ICC, Lukens MV, Gans ROB, Meijer K, Keus F. Eck RJ, et al. Sci Rep. 2022 Oct 18;12(1):17408. doi: 10.1038/s41598-022-21560-2. Sci Rep. 2022. PMID: 36257974 Free PMC article.

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