Shirani H - Search Results

1

Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer's disease.

Calvo-Rodriguez M, Kharitonova EK, Snyder AC, Hou SS, Sanchez-Mico MV, Das S, Fan Z, Shirani H, Nilsson KPR, Serrano-Pozo A, Bacskai BJ. Calvo-Rodriguez M, et al. Among authors: shirani h. Mol Neurodegener. 2024 Jan 18;19(1):6. doi: 10.1186/s13024-024-00702-2. Mol Neurodegener. 2024. PMID: 38238819 Free PMC article.

2

A new concise strategy for synthesis of dibenzo[b,f]thiepins and related fused symmetrical thiepin derivatives.

Shirani H, Janosik T. Shirani H, et al. J Org Chem. 2007 Nov 9;72(23):8984-6. doi: 10.1021/jo701627g. Epub 2007 Oct 12. J Org Chem. 2007. PMID: 17929979

3

Antifouling activity of synthesized peptide analogs of the sponge metabolite barettin.

Sjögren M, Johnson AL, Hedner E, Dahlström M, Göransson U, Shirani H, Bergman J, Jonsson PR, Bohlin L. Sjögren M, et al. Among authors: shirani h. Peptides. 2006 Sep;27(9):2058-64. doi: 10.1016/j.peptides.2006.03.027. Epub 2006 Jun 14. Peptides. 2006. PMID: 16781016

4

Synthesis and biological evaluation of fused thio- and selenopyrans as new indolocarbazole analogues with aryl hydrocarbon receptor affinity.

Wincent E, Shirani H, Bergman J, Rannug U, Janosik T. Wincent E, et al. Among authors: shirani h. Bioorg Med Chem. 2009 Feb 15;17(4):1648-53. doi: 10.1016/j.bmc.2008.12.072. Epub 2009 Jan 15. Bioorg Med Chem. 2009. PMID: 19186062

5

The structural basis for optimal performance of oligothiophene-based fluorescent amyloid ligands: conformational flexibility is essential for spectral assignment of a diversity of protein aggregates.

Klingstedt T, Shirani H, Åslund KO, Cairns NJ, Sigurdson CJ, Goedert M, Nilsson KP. Klingstedt T, et al. Among authors: shirani h. Chemistry. 2013 Jul 29;19(31):10179-92. doi: 10.1002/chem.201301463. Epub 2013 Jun 18. Chemistry. 2013. PMID: 23780508 Free PMC article.

6

Pentameric thiophene-based ligands that spectrally discriminate amyloid-β and tau aggregates display distinct solvatochromism and viscosity-induced spectral shifts.

Simon RA, Shirani H, Aslund KO, Bäck M, Haroutunian V, Gandy S, Nilsson KP. Simon RA, et al. Among authors: shirani h. Chemistry. 2014 Sep 22;20(39):12537-43. doi: 10.1002/chem.201402890. Epub 2014 Aug 8. Chemistry. 2014. PMID: 25111601 Free PMC article.

7

Distinct Spacing Between Anionic Groups: An Essential Chemical Determinant for Achieving Thiophene-Based Ligands to Distinguish β-Amyloid or Tau Polymorphic Aggregates.

Klingstedt T, Shirani H, Mahler J, Wegenast-Braun BM, Nyström S, Goedert M, Jucker M, Nilsson KP. Klingstedt T, et al. Among authors: shirani h. Chemistry. 2015 Jun 15;21(25):9072-82. doi: 10.1002/chem.201500556. Epub 2015 May 26. Chemistry. 2015. PMID: 26013403 Free PMC article.

8

A Palette of Fluorescent Thiophene-Based Ligands for the Identification of Protein Aggregates.

Shirani H, Linares M, Sigurdson CJ, Lindgren M, Norman P, Nilsson KP. Shirani H, et al. Chemistry. 2015 Oct 19;21(43):15133-7. doi: 10.1002/chem.201502999. Epub 2015 Sep 21. Chemistry. 2015. PMID: 26388448 Free PMC article.

9

Synthesis of Thiophene-Based Optical Ligands That Selectively Detect Tau Pathology in Alzheimer's Disease.

Shirani H, Appelqvist H, Bäck M, Klingstedt T, Cairns NJ, Nilsson KPR. Shirani H, et al. Chemistry. 2017 Dec 1;23(67):17127-17135. doi: 10.1002/chem.201703846. Epub 2017 Nov 8. Chemistry. 2017. PMID: 28926133 Free PMC article.

10

In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy.

Calvo-Rodriguez M, Hou SS, Snyder AC, Dujardin S, Shirani H, Nilsson KPR, Bacskai BJ. Calvo-Rodriguez M, et al. Among authors: shirani h. Acta Neuropathol Commun. 2019 Nov 8;7(1):171. doi: 10.1186/s40478-019-0832-1. Acta Neuropathol Commun. 2019. PMID: 31703739 Free PMC article.

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