Nilsson KPR - Search Results

1

Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer's disease.

Calvo-Rodriguez M, Kharitonova EK, Snyder AC, Hou SS, Sanchez-Mico MV, Das S, Fan Z, Shirani H, Nilsson KPR, Serrano-Pozo A, Bacskai BJ. Calvo-Rodriguez M, et al. Among authors: nilsson kpr. Mol Neurodegener. 2024 Jan 18;19(1):6. doi: 10.1186/s13024-024-00702-2. Mol Neurodegener. 2024. PMID: 38238819 Free PMC article.

2

The structural basis for optimal performance of oligothiophene-based fluorescent amyloid ligands: conformational flexibility is essential for spectral assignment of a diversity of protein aggregates.

Klingstedt T, Shirani H, Åslund KO, Cairns NJ, Sigurdson CJ, Goedert M, Nilsson KP. Klingstedt T, et al. Chemistry. 2013 Jul 29;19(31):10179-92. doi: 10.1002/chem.201301463. Epub 2013 Jun 18. Chemistry. 2013. PMID: 23780508 Free PMC article.

3

Pentameric thiophene-based ligands that spectrally discriminate amyloid-β and tau aggregates display distinct solvatochromism and viscosity-induced spectral shifts.

Simon RA, Shirani H, Aslund KO, Bäck M, Haroutunian V, Gandy S, Nilsson KP. Simon RA, et al. Chemistry. 2014 Sep 22;20(39):12537-43. doi: 10.1002/chem.201402890. Epub 2014 Aug 8. Chemistry. 2014. PMID: 25111601 Free PMC article.

4

Distinct Spacing Between Anionic Groups: An Essential Chemical Determinant for Achieving Thiophene-Based Ligands to Distinguish β-Amyloid or Tau Polymorphic Aggregates.

Klingstedt T, Shirani H, Mahler J, Wegenast-Braun BM, Nyström S, Goedert M, Jucker M, Nilsson KP. Klingstedt T, et al. Chemistry. 2015 Jun 15;21(25):9072-82. doi: 10.1002/chem.201500556. Epub 2015 May 26. Chemistry. 2015. PMID: 26013403 Free PMC article.

5

A Palette of Fluorescent Thiophene-Based Ligands for the Identification of Protein Aggregates.

Shirani H, Linares M, Sigurdson CJ, Lindgren M, Norman P, Nilsson KP. Shirani H, et al. Chemistry. 2015 Oct 19;21(43):15133-7. doi: 10.1002/chem.201502999. Epub 2015 Sep 21. Chemistry. 2015. PMID: 26388448 Free PMC article.

6

Synthesis of Thiophene-Based Optical Ligands That Selectively Detect Tau Pathology in Alzheimer's Disease.

Shirani H, Appelqvist H, Bäck M, Klingstedt T, Cairns NJ, Nilsson KPR. Shirani H, et al. Among authors: nilsson kpr. Chemistry. 2017 Dec 1;23(67):17127-17135. doi: 10.1002/chem.201703846. Epub 2017 Nov 8. Chemistry. 2017. PMID: 28926133 Free PMC article.

7

In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy.

Calvo-Rodriguez M, Hou SS, Snyder AC, Dujardin S, Shirani H, Nilsson KPR, Bacskai BJ. Calvo-Rodriguez M, et al. Among authors: nilsson kpr. Acta Neuropathol Commun. 2019 Nov 8;7(1):171. doi: 10.1186/s40478-019-0832-1. Acta Neuropathol Commun. 2019. PMID: 31703739 Free PMC article.

8

Synthesis and Characterization of Thiophene-based Donor-Acceptor-Donor Heptameric Ligands for Spectral Assignment of Polymorphic Amyloid-β Deposits.

Lantz L, Shirani H, Klingstedt T, Nilsson KPR. Lantz L, et al. Among authors: nilsson kpr. Chemistry. 2020 Jun 10;26(33):7425-7432. doi: 10.1002/chem.201905612. Epub 2020 May 15. Chemistry. 2020. PMID: 32022335 Free PMC article.

9

Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy.

Shahnawaz M, Mukherjee A, Pritzkow S, Mendez N, Rabadia P, Liu X, Hu B, Schmeichel A, Singer W, Wu G, Tsai AL, Shirani H, Nilsson KPR, Low PA, Soto C. Shahnawaz M, et al. Among authors: nilsson kpr. Nature. 2020 Feb;578(7794):273-277. doi: 10.1038/s41586-020-1984-7. Epub 2020 Feb 5. Nature. 2020. PMID: 32025029 Free PMC article.

10

Optotracing for selective fluorescence-based detection, visualization and quantification of live S. aureus in real-time.

Butina K, Tomac A, Choong FX, Shirani H, Nilsson KPR, Löffler S, Richter-Dahlfors A. Butina K, et al. Among authors: nilsson kpr. NPJ Biofilms Microbiomes. 2020 Oct 9;6(1):35. doi: 10.1038/s41522-020-00150-y. NPJ Biofilms Microbiomes. 2020. PMID: 33037198 Free PMC article.

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