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Neoadjuvant trastuzumab deruxtecan (T-DXd) with response-directed definitive therapy in early stage HER2-positive breast cancer: a phase II study protocol (SHAMROCK study).
Dowling GP, Toomey S, Bredin P, Parker I, Mulroe E, Marron J, McLoughlin O, Teiserskiene A, Power C, O'Shea AM, Greally M, Morris PG, Duke D, Hill ADK, Hennessy BT. Dowling GP, et al. Among authors: toomey s. BMC Cancer. 2024 Jan 17;24(1):91. doi: 10.1186/s12885-024-11851-4. BMC Cancer. 2024. PMID: 38233810 Free PMC article.
Inter-organ proteomic analysis reveals insights into the molecular mechanisms underlying the anti-diabetic effects of cis-9, trans-11-conjugated linoleic acid in ob/ob mice.
Rungapamestry V, McMonagle J, Reynolds C, Rucklidge G, Reid M, Duncan G, Ross K, Horgan G, Toomey S, Moloney AP, Roos Bd, Roche HM. Rungapamestry V, et al. Among authors: toomey s. Proteomics. 2012 Feb;12(3):461-76. doi: 10.1002/pmic.201100312. Epub 2012 Jan 18. Proteomics. 2012. PMID: 22144173
Transcriptomic coordination in the human metabolic network reveals links between n-3 fat intake, adipose tissue gene expression and metabolic health.
Morine MJ, Tierney AC, van Ommen B, Daniel H, Toomey S, Gjelstad IM, Gormley IC, Pérez-Martinez P, Drevon CA, López-Miranda J, Roche HM. Morine MJ, et al. Among authors: toomey s. PLoS Comput Biol. 2011 Nov;7(11):e1002223. doi: 10.1371/journal.pcbi.1002223. Epub 2011 Nov 3. PLoS Comput Biol. 2011. PMID: 22072950 Free PMC article. Clinical Trial.
The frequencies and clinical implications of mutations in 33 kinase-related genes in locally advanced rectal cancer: a pilot study.
Abdul-Jalil KI, Sheehan KM, Toomey S, Schmid J, Prehn J, O'Grady A, Cummins R, O'Neill B, McNamara DA, Deasy J, Breathnach O, Grogan L, Rogers A, Doherty G, Winter D, Ryan J, El-Masry S, Gibbons D, Sheahan K, Gillen P, Kay EW, Hennessy BT. Abdul-Jalil KI, et al. Among authors: toomey s. Ann Surg Oncol. 2014 Aug;21(8):2642-9. doi: 10.1245/s10434-014-3658-x. Epub 2014 Apr 4. Ann Surg Oncol. 2014. PMID: 24700299
Immune effects of bevacizumab: killing two birds with one stone.
Elamin YY, Rafee S, Toomey S, Hennessy BT. Elamin YY, et al. Among authors: toomey s. Cancer Microenviron. 2015 Apr;8(1):15-21. doi: 10.1007/s12307-014-0160-8. Epub 2014 Oct 18. Cancer Microenviron. 2015. PMID: 25326055 Free PMC article.
A preclinical evaluation of the PI3K alpha/delta dominant inhibitor BAY 80-6946 in HER2-positive breast cancer models with acquired resistance to the HER2-targeted therapies trastuzumab and lapatinib.
Elster N, Cremona M, Morgan C, Toomey S, Carr A, O'Grady A, Hennessy BT, Eustace AJ. Elster N, et al. Among authors: toomey s. Breast Cancer Res Treat. 2015 Jan;149(2):373-83. doi: 10.1007/s10549-014-3239-5. Epub 2014 Dec 21. Breast Cancer Res Treat. 2015. PMID: 25528022
165 results