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Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1.
Ozawa T, Ikeda Y, Chen L, Suzuki R, Hoshino A, Noguchi A, Kita S, Anraku Y, Igarashi E, Saga Y, Inasaki N, Taminishi S, Sasaki J, Kirita Y, Fukuhara H, Maenaka K, Hashiguchi T, Fukuhara T, Hirabayashi K, Tani H, Kishi H, Niimi H. Ozawa T, et al. Among authors: taminishi s. Structure. 2024 Mar 7;32(3):263-272.e7. doi: 10.1016/j.str.2023.12.013. Epub 2024 Jan 15. Structure. 2024. PMID: 38228146
Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants.
Moriyama S, Anraku Y, Taminishi S, Adachi Y, Kuroda D, Kita S, Higuchi Y, Kirita Y, Kotaki R, Tonouchi K, Yumoto K, Suzuki T, Someya T, Fukuhara H, Kuroda Y, Yamamoto T, Onodera T, Fukushi S, Maeda K, Nakamura-Uchiyama F, Hashiguchi T, Hoshino A, Maenaka K, Takahashi Y. Moriyama S, et al. Among authors: taminishi s. Nat Commun. 2023 Jul 14;14(1):4198. doi: 10.1038/s41467-023-39890-8. Nat Commun. 2023. PMID: 37452031 Free PMC article.
An engineered ACE2 decoy neutralizes the SARS-CoV-2 Omicron variant and confers protection against infection in vivo.
Ikemura N, Taminishi S, Inaba T, Arimori T, Motooka D, Katoh K, Kirita Y, Higuchi Y, Li S, Suzuki T, Itoh Y, Ozaki Y, Nakamura S, Matoba S, Standley DM, Okamoto T, Takagi J, Hoshino A. Ikemura N, et al. Among authors: taminishi s. Sci Transl Med. 2022 Jun 22;14(650):eabn7737. doi: 10.1126/scitranslmed.abn7737. Epub 2022 Jun 22. Sci Transl Med. 2022. PMID: 35471044 Free PMC article.
Orotic acid protects pancreatic β cell by p53 inactivation in diabetic mouse model.
Fushimura Y, Hoshino A, Furukawa S, Nakagawa T, Hino T, Taminishi S, Minami Y, Urata R, Iwai-Kanai E, Matoba S. Fushimura Y, et al. Among authors: taminishi s. Biochem Biophys Res Commun. 2021 Dec 31;585:191-195. doi: 10.1016/j.bbrc.2021.10.060. Epub 2021 Oct 29. Biochem Biophys Res Commun. 2021. PMID: 34813979
Energy-sparing by 2-methyl-2-thiazoline protects heart from ischaemia/reperfusion injury.
Nishi M, Ogata T, Kobayakawa K, Kobayakawa R, Matsuo T, Cannistraci CV, Tomita S, Taminishi S, Suga T, Kitani T, Higuchi Y, Sakamoto A, Tsuji Y, Soga T, Matoba S. Nishi M, et al. Among authors: taminishi s. ESC Heart Fail. 2022 Feb;9(1):428-441. doi: 10.1002/ehf2.13732. Epub 2021 Dec 2. ESC Heart Fail. 2022. PMID: 34854235 Free PMC article.
Modest dilation using rotational atherectomy and drug-coated balloon for native coronary proximal lesion with patent internal thoracic artery graft.
Shiraishi J, Mabuchi T, Kajihara T, Ukawa R, Nishimura T, Ohkura T, Taminishi S, Tsuji Y, Saburi M, Takigami M, Tsubakimoto Y, Inoue K, Ishibashi K. Shiraishi J, et al. Among authors: taminishi s. J Cardiol Cases. 2024 Aug 29;30(6):196-200. doi: 10.1016/j.jccase.2024.08.005. eCollection 2024 Dec. J Cardiol Cases. 2024. PMID: 39697690 Free PMC article.
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