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Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1.
Ozawa T, Ikeda Y, Chen L, Suzuki R, Hoshino A, Noguchi A, Kita S, Anraku Y, Igarashi E, Saga Y, Inasaki N, Taminishi S, Sasaki J, Kirita Y, Fukuhara H, Maenaka K, Hashiguchi T, Fukuhara T, Hirabayashi K, Tani H, Kishi H, Niimi H. Ozawa T, et al. Among authors: fukuhara t, fukuhara h. Structure. 2024 Mar 7;32(3):263-272.e7. doi: 10.1016/j.str.2023.12.013. Epub 2024 Jan 15. Structure. 2024. PMID: 38228146
Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant.
Saito A, Tamura T, Zahradnik J, Deguchi S, Tabata K, Anraku Y, Kimura I, Ito J, Yamasoba D, Nasser H, Toyoda M, Nagata K, Uriu K, Kosugi Y, Fujita S, Shofa M, Monira Begum M, Shimizu R, Oda Y, Suzuki R, Ito H, Nao N, Wang L, Tsuda M, Yoshimatsu K, Kuramochi J, Kita S, Sasaki-Tabata K, Fukuhara H, Maenaka K, Yamamoto Y, Nagamoto T, Asakura H, Nagashima M, Sadamasu K, Yoshimura K, Ueno T, Schreiber G, Takaori-Kondo A; Genotype to Phenotype Japan (G2P-Japan) Consortium; Shirakawa K, Sawa H, Irie T, Hashiguchi T, Takayama K, Matsuno K, Tanaka S, Ikeda T, Fukuhara T, Sato K. Saito A, et al. Among authors: fukuhara t, fukuhara h. Cell Host Microbe. 2022 Nov 9;30(11):1540-1555.e15. doi: 10.1016/j.chom.2022.10.003. Epub 2022 Oct 18. Cell Host Microbe. 2022. PMID: 36272413 Free PMC article.
A third dose of the BNT162b2 mRNA vaccine sufficiently improves the neutralizing activity against SARS-CoV-2 variants in liver transplant recipients.
Tomiyama T, Suzuki R, Harada N, Tamura T, Toshida K, Kosai-Fujimoto Y, Tomino T, Yoshiya S, Nagao Y, Takeishi K, Itoh S, Kobayashi N, Ito H, Yoshio S, Kanto T, Yoshizumi T, Fukuhara T. Tomiyama T, et al. Among authors: fukuhara t. Front Cell Infect Microbiol. 2023 May 16;13:1197349. doi: 10.3389/fcimb.2023.1197349. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37260700 Free PMC article.
Impact of Imprinted Immunity Induced by mRNA Vaccination in an Experimental Animal Model.
Fujita S, Uriu K, Pan L, Nao N, Tabata K, Kishimoto M, Itakura Y, Sawa H, Kida I, Tamura T; Genotype to Phenotype Japan (G2P-Japan) Consortium; Fukuhara T, Ito J, Matsuno K, Sato K. Fujita S, et al. Among authors: fukuhara t. J Infect Dis. 2023 Oct 18;228(8):1060-1065. doi: 10.1093/infdis/jiad230. J Infect Dis. 2023. PMID: 37369369 Free PMC article.
Inhibitors of cannabinoid receptor 1 suppress the cellular entry of Lujo virus.
Kimura M, Matsuoka R, Taniguchi S, Maruyama J, Paessler S, Oka S, Yamashita A, Fukuhara T, Matsuura Y, Tani H. Kimura M, et al. Among authors: fukuhara t. Virology. 2023 Oct;587:109867. doi: 10.1016/j.virol.2023.109867. Epub 2023 Aug 10. Virology. 2023. PMID: 37633192 Free article.
High-precision rapid testing of omicron SARS-CoV-2 variants in clinical samples using AI-nanopore.
Murakami K, Kubota SI, Tanaka K, Tanaka H, Akabane K, Suzuki R, Shinohara Y, Takei H, Hashimoto S, Tanaka Y, Hojyo S, Sakamoto O, Naono N, Takaai T, Sato K, Kojima Y, Harada T, Hattori T, Fuke S, Yokota I, Konno S, Washio T, Fukuhara T, Teshima T, Taniguchi M, Murakami M. Murakami K, et al. Among authors: fukuhara t. Lab Chip. 2023 Nov 7;23(22):4909-4918. doi: 10.1039/d3lc00572k. Lab Chip. 2023. PMID: 37877206
Characteristics of the SARS-CoV-2 omicron HK.3 variant harbouring the FLip substitution.
Kosugi Y, Plianchaisuk A, Putri O, Uriu K, Kaku Y, Hinay AA Jr, Chen L, Kuramochi J, Sadamasu K, Yoshimura K, Asakura H, Nagashima M, Ito J; Genotype to Phenotype Japan (G2P-Japan) Consortium; Sato K. Kosugi Y, et al. Lancet Microbe. 2024 Apr;5(4):e313. doi: 10.1016/S2666-5247(23)00373-7. Epub 2024 Jan 11. Lancet Microbe. 2024. PMID: 38219759 Free article. No abstract available.
Virological characteristics of the SARS-CoV-2 BA.2.86 variant.
Tamura T, Mizuma K, Nasser H, Deguchi S, Padilla-Blanco M, Oda Y, Uriu K, Tolentino JEM, Tsujino S, Suzuki R, Kojima I, Nao N, Shimizu R, Wang L, Tsuda M, Jonathan M, Kosugi Y, Guo Z, Hinay AA Jr, Putri O, Kim Y, Tanaka YL, Asakura H, Nagashima M, Sadamasu K, Yoshimura K; Genotype to Phenotype Japan (G2P-Japan) Consortium; Saito A, Ito J, Irie T, Tanaka S, Zahradnik J, Ikeda T, Takayama K, Matsuno K, Fukuhara T, Sato K. Tamura T, et al. Among authors: fukuhara t. Cell Host Microbe. 2024 Feb 14;32(2):170-180.e12. doi: 10.1016/j.chom.2024.01.001. Epub 2024 Jan 26. Cell Host Microbe. 2024. PMID: 38280382 Free article.
828 results