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Page 1
APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease.
Datta S, Antonio BM, Zahler NH, Theile JW, Krafte D, Zhang H, Rosenberg PB, Chaves AB, Muoio DM, Zhang G, Silas D, Li G, Soldano K, Nystrom S, Ferreira D, Miller SE, Bain JR, Muehlbauer MJ, Ilkayeva O, Becker TC, Hohmeier HE, Newgard CB, Olabisi OA. Datta S, et al. Among authors: antonio bm. J Clin Invest. 2024 Jan 16;134(5):e172262. doi: 10.1172/JCI172262. J Clin Invest. 2024. PMID: 38227370 Free PMC article.
TRPA1 ankyrin repeat six interacts with a small molecule inhibitor chemotype.
Tseng WC, Pryde DC, Yoger KE, Padilla KM, Antonio BM, Han S, Shanmugasundaram V, Gerlach AC. Tseng WC, et al. Among authors: antonio bm. Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):12301-12306. doi: 10.1073/pnas.1808142115. Epub 2018 Nov 14. Proc Natl Acad Sci U S A. 2018. PMID: 30429323 Free PMC article.
A comprehensive approach to identifying repurposed drugs to treat SCN8A epilepsy.
Atkin TA, Maher CM, Gerlach AC, Gay BC, Antonio BM, Santos SC, Padilla KM, Rader J, Krafte DS, Fox MA, Stewart GR, Petrovski S, Devinsky O, Might M, Petrou S, Goldstein DB. Atkin TA, et al. Among authors: antonio bm. Epilepsia. 2018 Apr;59(4):802-813. doi: 10.1111/epi.14037. Epub 2018 Mar 25. Epilepsia. 2018. PMID: 29574705
Discovery and in Vitro Optimization of 3-Sulfamoylbenzamides as ROMK Inhibitors.
Sammons MF, Kharade SV, Filipski KJ, Boehm M, Smith AC, Shavnya A, Fernando DP, Dowling MS, Carpino PA, Castle NA, Zellmer SG, Antonio BM, Gosset JR, Carlo A, Denton JS. Sammons MF, et al. Among authors: antonio bm. ACS Med Chem Lett. 2018 Jan 19;9(2):125-130. doi: 10.1021/acsmedchemlett.7b00481. eCollection 2018 Feb 8. ACS Med Chem Lett. 2018. PMID: 29456800 Free PMC article.
GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K2P ) channel opener, reduces rat dorsal root ganglion neuron excitability.
Loucif AJC, Saintot PP, Liu J, Antonio BM, Zellmer SG, Yoger K, Veale EL, Wilbrey A, Omoto K, Cao L, Gutteridge A, Castle NA, Stevens EB, Mathie A. Loucif AJC, et al. Among authors: antonio bm. Br J Pharmacol. 2018 Jun;175(12):2272-2283. doi: 10.1111/bph.14098. Epub 2017 Dec 29. Br J Pharmacol. 2018. PMID: 29150838 Free PMC article.
Validation of ion channel targets.
Gerlach AC, Antonio BM. Gerlach AC, et al. Among authors: antonio bm. Channels (Austin). 2015;9(6):376-9. doi: 10.1080/19336950.2015.1081725. Epub 2015 Nov 10. Channels (Austin). 2015. PMID: 26556675 Free PMC article. Review.
A novel selective and orally bioavailable Nav 1.8 channel blocker, PF-01247324, attenuates nociception and sensory neuron excitability.
Payne CE, Brown AR, Theile JW, Loucif AJ, Alexandrou AJ, Fuller MD, Mahoney JH, Antonio BM, Gerlach AC, Printzenhoff DM, Prime RL, Stockbridge G, Kirkup AJ, Bannon AW, England S, Chapman ML, Bagal S, Roeloffs R, Anand U, Anand P, Bungay PJ, Kemp M, Butt RP, Stevens EB. Payne CE, et al. Among authors: antonio bm. Br J Pharmacol. 2015 May;172(10):2654-70. doi: 10.1111/bph.13092. Epub 2015 Apr 10. Br J Pharmacol. 2015. PMID: 25625641 Free PMC article.
Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels.
McCormack K, Santos S, Chapman ML, Krafte DS, Marron BE, West CW, Krambis MJ, Antonio BM, Zellmer SG, Printzenhoff D, Padilla KM, Lin Z, Wagoner PK, Swain NA, Stupple PA, de Groot M, Butt RP, Castle NA. McCormack K, et al. Among authors: antonio bm. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):E2724-32. doi: 10.1073/pnas.1220844110. Epub 2013 Jul 1. Proc Natl Acad Sci U S A. 2013. PMID: 23818614 Free PMC article.