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Gold(I) ion and the phosphine ligand are necessary for the anti-Toxoplasma gondii activity of auranofin.
Microbiol Spectr. 2024 Feb 6;12(2):e0296823. doi: 10.1128/spectrum.02968-23. Epub 2024 Jan 11.
Microbiol Spectr. 2024.
PMID: 38206030
Free PMC article.
Auranofin Resistance in Toxoplasma gondii Decreases the Accumulation of Reactive Oxygen Species but Does Not Target Parasite Thioredoxin Reductase.
Ma CI, Tirtorahardjo JA, Jan S, Schweizer SS, Rosario SAC, Du Y, Zhang JJ, Morrissette NS, Andrade RM.
Ma CI, et al. Among authors: tirtorahardjo ja.
Front Cell Infect Microbiol. 2021 Mar 19;11:618994. doi: 10.3389/fcimb.2021.618994. eCollection 2021.
Front Cell Infect Microbiol. 2021.
PMID: 33816332
Free PMC article.
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