Fiedler M - Search Results

1

Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism.

Dunkelmann DL, Piedrafita C, Dickson A, Liu KC, Elliott TS, Fiedler M, Bellini D, Zhou A, Cervettini D, Chin JW. Dunkelmann DL, et al. Among authors: fiedler m. Nature. 2024 Jan;625(7995):603-610. doi: 10.1038/s41586-023-06897-6. Epub 2024 Jan 10. Nature. 2024. PMID: 38200312 Free PMC article.

2

Mechanism-based traps enable protease and hydrolase substrate discovery.

Tang S, Beattie AT, Kafkova L, Petris G, Huguenin-Dezot N, Fiedler M, Freeman M, Chin JW. Tang S, et al. Among authors: fiedler m. Nature. 2022 Feb;602(7898):701-707. doi: 10.1038/s41586-022-04414-9. Epub 2022 Feb 16. Nature. 2022. PMID: 35173328 Free PMC article.

3

Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization.

Madrzak J, Fiedler M, Johnson CM, Ewan R, Knebel A, Bienz M, Chin JW. Madrzak J, et al. Among authors: fiedler m. Nat Commun. 2015 Apr 24;6:6718. doi: 10.1038/ncomms7718. Nat Commun. 2015. PMID: 25907794 Free PMC article.

4

Arabidopsis FLL2 promotes liquid-liquid phase separation of polyadenylation complexes.

Fang X, Wang L, Ishikawa R, Li Y, Fiedler M, Liu F, Calder G, Rowan B, Weigel D, Li P, Dean C. Fang X, et al. Among authors: fiedler m. Nature. 2019 May;569(7755):265-269. doi: 10.1038/s41586-019-1165-8. Epub 2019 May 1. Nature. 2019. PMID: 31043738 Free PMC article.

5

Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas.

Krishnan A, Berthelet J, Renaud E, Rosigkeit S, Distler U, Stawiski E, Wang J, Modrusan Z, Fiedler M, Bienz M, Tenzer S, Schad A, Roth W, Thiede B, Seshagiri S, Musholt TJ, Rajalingam K. Krishnan A, et al. Among authors: fiedler m. Nat Commun. 2020 Apr 28;11(1):2056. doi: 10.1038/s41467-020-15955-w. Nat Commun. 2020. PMID: 32345963 Free PMC article.

6

The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization.

Schwarz-Romond T, Fiedler M, Shibata N, Butler PJ, Kikuchi A, Higuchi Y, Bienz M. Schwarz-Romond T, et al. Among authors: fiedler m. Nat Struct Mol Biol. 2007 Jun;14(6):484-92. doi: 10.1038/nsmb1247. Epub 2007 May 27. Nat Struct Mol Biol. 2007. PMID: 17529994

7

Biophysical Survey of Small-Molecule β-Catenin Inhibitors: A Cautionary Tale.

McCoy MA, Spicer D, Wells N, Hoogewijs K, Fiedler M, Baud MGJ. McCoy MA, et al. Among authors: fiedler m. J Med Chem. 2022 May 26;65(10):7246-7261. doi: 10.1021/acs.jmedchem.2c00228. Epub 2022 May 17. J Med Chem. 2022. PMID: 35581674 Free PMC article. Review.

8

Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.

Renko M, Fiedler M, Rutherford TJ, Schaefer JV, Plückthun A, Bienz M. Renko M, et al. Among authors: fiedler m. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):20977-20983. doi: 10.1073/pnas.1912705116. Epub 2019 Sep 30. Proc Natl Acad Sci U S A. 2019. PMID: 31570581 Free PMC article.

9

Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.

Fiedler M, Franco-Echevarría E, Schulten A, Nielsen M, Rutherford TJ, Yeates A, Ahsan B, Dean C, Bienz M. Fiedler M, et al. Cell Rep. 2022 Nov 8;41(6):111607. doi: 10.1016/j.celrep.2022.111607. Cell Rep. 2022. PMID: 36351412 Free PMC article.

10

Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity.

Franco-Echevarría E, Rutherford TJ, Fiedler M, Dean C, Bienz M. Franco-Echevarría E, et al. Among authors: fiedler m. J Biol Chem. 2022 Nov;298(11):102540. doi: 10.1016/j.jbc.2022.102540. Epub 2022 Sep 27. J Biol Chem. 2022. PMID: 36174674 Free PMC article.

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