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Page 1
Affinity fine-tuning anti-CAIX CAR-T cells mitigate on-target off-tumor side effects.
Wang Y, Buck A, Piel B, Zerefa L, Murugan N, Coherd CD, Miklosi AG, Johal H, Bastos RN, Huang K, Ficial M, Laimon YN, Signoretti S, Zhong Z, Hoang SM, Kastrunes GM, Grimaud M, Fayed A, Yuan HC, Nguyen QD, Thai T, Ivanova EV, Paweletz CP, Wu MR, Choueiri TK, Wee JO, Freeman GJ, Barbie DA, Marasco WA. Wang Y, et al. Among authors: kastrunes gm. Mol Cancer. 2024 Mar 16;23(1):56. doi: 10.1186/s12943-024-01952-w. Mol Cancer. 2024. PMID: 38491381 Free PMC article.
Immune-restoring CAR-T cells display antitumor activity and reverse immunosuppressive TME in a humanized ccRCC mouse model.
Wang Y, Cho JW, Kastrunes G, Buck A, Razimbaud C, Culhane AC, Sun J, Braun DA, Choueiri TK, Wu CJ, Jones K, Nguyen QD, Zhu Z, Wei K, Zhu Q, Signoretti S, Freeman GJ, Hemberg M, Marasco WA. Wang Y, et al. Among authors: kastrunes g. iScience. 2024 Jan 15;27(2):108879. doi: 10.1016/j.isci.2024.108879. eCollection 2024 Feb 16. iScience. 2024. PMID: 38327771 Free PMC article.
Evolution of cell therapy for renal cell carcinoma.
Wang Y, Suarez ER, Kastrunes G, de Campos NSP, Abbas R, Pivetta RS, Murugan N, Chalbatani GM, D'Andrea V, Marasco WA. Wang Y, et al. Among authors: kastrunes g. Mol Cancer. 2024 Jan 9;23(1):8. doi: 10.1186/s12943-023-01911-x. Mol Cancer. 2024. PMID: 38195534 Free PMC article. Review.
Preclinical models for development of immune-oncology therapies.
Wang Y, Shelton SE, Kastrunes G, Barbie DA, Freeman GJ, Marasco WA. Wang Y, et al. Among authors: kastrunes g. Immuno-oncol Insights. 2022;3(8):379-398. doi: 10.18609/ioi.2022.41. Epub 2022 Sep 26. Immuno-oncol Insights. 2022. PMID: 37132013 Free PMC article.