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Phosphorylation at serine 214 correlates with tau seeding activity in an age-dependent manner in two mouse models for tauopathies and is required for tau transsynaptic propagation.
Martinez P, Jury-Garfe N, Patel H, You Y, Perkins A, You Y, Lee-Gosselin A, Vidal R, Lasagna-Reeves CA. Martinez P, et al. Among authors: lee gosselin a. bioRxiv [Preprint]. 2024 Jul 23:2024.07.22.604618. doi: 10.1101/2024.07.22.604618. bioRxiv. 2024. PMID: 39211286 Free PMC article. Preprint.
Inpp5d haplodeficiency alleviates tau pathology in the PS19 mouse model of Tauopathy.
Soni DM, Lin PB, Lee-Gosselin A, Lloyd CD, Mason E, Ingraham CM, Perkins A, Moutinho M, Lamb BT, Chu S, Oblak AL. Soni DM, et al. Among authors: lee gosselin a. Alzheimers Dement. 2024 Jul;20(7):4985-4998. doi: 10.1002/alz.14078. Epub 2024 Jun 26. Alzheimers Dement. 2024. PMID: 38923171 Free PMC article.
In vivo validation of late-onset Alzheimer's disease genetic risk factors.
Sasner M, Preuss C, Pandey RS, Uyar A, Garceau D, Kotredes KP, Williams H, Oblak AL, Lin PB, Perkins B, Soni D, Ingraham C, Lee-Gosselin A, Lamb BT, Howell GR, Carter GW. Sasner M, et al. Among authors: lee gosselin a. Alzheimers Dement. 2024 Jul;20(7):4970-4984. doi: 10.1002/alz.13840. Epub 2024 Apr 30. Alzheimers Dement. 2024. PMID: 38687251 Free PMC article.
In vivo validation of late-onset Alzheimer's disease genetic risk factors.
Sasner M, Preuss C, Pandey RS, Uyar A, Garceau D, Kotredes KP, Williams H, Oblak AL, Lin PB, Perkins B, Soni D, Ingraham C, Lee-Gosselin A, Lamb BT, Howell GR, Carter GW. Sasner M, et al. Among authors: lee gosselin a. bioRxiv [Preprint]. 2023 Dec 24:2023.12.21.572849. doi: 10.1101/2023.12.21.572849. bioRxiv. 2023. Update in: Alzheimers Dement. 2024 Jul;20(7):4970-4984. doi: 10.1002/alz.13840 PMID: 38187758 Free PMC article. Updated. Preprint.
TREM2-Deficient Microglia Attenuate Tau Spreading In Vivo.
Lee-Gosselin A, Jury-Garfe N, You Y, Dabin L, Soni D, Dutta S, Rochet JC, Kim J, Oblak AL, Lasagna-Reeves CA. Lee-Gosselin A, et al. Cells. 2023 Jun 10;12(12):1597. doi: 10.3390/cells12121597. Cells. 2023. PMID: 37371067 Free PMC article.
TONSL Is an Immortalizing Oncogene and a Therapeutic Target in Breast Cancer.
Khatpe AS, Dirks R, Bhat-Nakshatri P, Mang H, Batic K, Swiezy S, Olson J, Rao X, Wang Y, Tanaka H, Liu S, Wan J, Chen D, Liu Y, Fang F, Althouse S, Hulsey E, Granatir MM, Addison R, Temm CJ, Sandusky G, Lee-Gosselin A, Nephew K, Miller KD, Nakshatri H. Khatpe AS, et al. Among authors: lee gosselin a. Cancer Res. 2023 Apr 14;83(8):1345-1360. doi: 10.1158/0008-5472.CAN-22-3667. Cancer Res. 2023. PMID: 37057595 Free PMC article.
Bassoon contributes to tau-seed propagation and neurotoxicity.
Martinez P, Patel H, You Y, Jury N, Perkins A, Lee-Gosselin A, Taylor X, You Y, Viana Di Prisco G, Huang X, Dutta S, Wijeratne AB, Redding-Ochoa J, Shahid SS, Codocedo JF, Min S, Landreth GE, Mosley AL, Wu YC, McKinzie DL, Rochet JC, Zhang J, Atwood BK, Troncoso J, Lasagna-Reeves CA. Martinez P, et al. Among authors: lee gosselin a. Nat Neurosci. 2022 Dec;25(12):1597-1607. doi: 10.1038/s41593-022-01191-6. Epub 2022 Nov 7. Nat Neurosci. 2022. PMID: 36344699 Free PMC article.
Ultrasound-controllable engineered bacteria for cancer immunotherapy.
Abedi MH, Yao MS, Mittelstein DR, Bar-Zion A, Swift MB, Lee-Gosselin A, Barturen-Larrea P, Buss MT, Shapiro MG. Abedi MH, et al. Among authors: lee gosselin a. Nat Commun. 2022 Mar 24;13(1):1585. doi: 10.1038/s41467-022-29065-2. Nat Commun. 2022. PMID: 35332124 Free PMC article.
33 results