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Substrate identification and specificity profiling of deubiquitylases against endogenously-generated ubiquitin-protein conjugates.
Rossio V, Paulo JA, Liu X, Gygi SP, King RW. Rossio V, et al. Among authors: gygi sp. bioRxiv [Preprint]. 2023 Dec 20:2023.12.20.572581. doi: 10.1101/2023.12.20.572581. bioRxiv. 2023. Update in: Cell Chem Biol. 2024 Jul 18;31(7):1349-1362.e5. doi: 10.1016/j.chembiol.2024.05.001 PMID: 38187689 Free PMC article. Updated. Preprint.
Proteostasis and lysosomal quality control deficits in Alzheimer's disease neurons.
Chou CC, Vest R, Prado MA, Wilson-Grady J, Paulo JA, Shibuya Y, Moran-Losada P, Lee TT, Luo J, Gygi SP, Kelly JW, Finley D, Wernig M, Wyss-Coray T, Frydman J. Chou CC, et al. Among authors: gygi sp. bioRxiv [Preprint]. 2023 Mar 27:2023.03.27.534444. doi: 10.1101/2023.03.27.534444. bioRxiv. 2023. PMID: 37034684 Free PMC article. Preprint.
Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.
Mitchell W, Goeminne LJE, Tyshkovskiy A, Zhang S, Chen JY, Paulo JA, Pierce KA, Choy AH, Clish CB, Gygi SP, Gladyshev VN. Mitchell W, et al. Among authors: gygi sp. bioRxiv [Preprint]. 2023 Nov 27:2023.06.30.546730. doi: 10.1101/2023.06.30.546730. bioRxiv. 2023. Update in: Elife. 2024 Mar 22;12:RP90579. doi: 10.7554/eLife.90579 PMID: 37425825 Free PMC article. Updated. Preprint.
ALS-related p97 R155H mutation disrupts lysophagy in iPSC-derived motor neurons.
Klickstein JA, Johnson MA, Antonoudiou P, Maguire J, Paulo JA, Gygi SP, Weihl C, Raman M. Klickstein JA, et al. Among authors: gygi sp. Stem Cell Reports. 2024 Mar 12;19(3):366-382. doi: 10.1016/j.stemcr.2024.01.002. Epub 2024 Feb 8. Stem Cell Reports. 2024. PMID: 38335961 Free PMC article.
721 results