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Spatial analysis of NOS2 and COX2 interaction with T-effector cells reveals immunosuppressive landscapes associated with poor outcome in ER- breast cancer patients.
Ridnour LA, Cheng RYS, Heinz WF, Pore M, Gonzalez AL, Femino EL, Moffat R, Wink AL, Imtiaz F, Coutinho L, Butcher D, Edmondson EF, Rangel MC, Wong STC, Lipkowitz S, Glynn S, Vitek MP, McVicar DW, Li X, Anderson SK, Paolocci N, Hewitt SM, Ambs S, Billiar TR, Chang JC, Lockett SJ, Wink DA. Ridnour LA, et al. Among authors: chang jc. bioRxiv [Preprint]. 2023 Dec 23:2023.12.21.572867. doi: 10.1101/2023.12.21.572867. bioRxiv. 2023. PMID: 38187660 Free PMC article. Preprint.
Interferon-gamma is Quintessential for NOS2 and COX2 Expression in ER - Breast Tumors that Lead to Poor Outcome.
Cheng RY, Ridnour LA, Wink AL, Gonzalez AL, Femino EL, Rittscher H, Somasundarum V, Heinz WF, Coutinho L, Cristina Rangel M, Edmondson EF, Butcher D, Kinders RJ, Li X, Wong STC, McVicar DW, Anderson SK, Pore M, Hewitt SM, Billiar TR, Glynn S, Chang JC, Lockett SJ, Ambs S, Wink DA. Cheng RY, et al. Among authors: chang jc. bioRxiv [Preprint]. 2023 Apr 6:2023.04.06.535916. doi: 10.1101/2023.04.06.535916. bioRxiv. 2023. Update in: Cell Death Dis. 2023 May 11;14(5):319. doi: 10.1038/s41419-023-05834-9 PMID: 37066331 Free PMC article. Updated. Preprint.
NOS2 and COX2 Provide Key Spatial Targets that Determine Outcome in ER- Breast Cancer.
Ridnour LA, Heinz WF, Cheng RY, Wink AL, Kedei N, Pore M, Imtiaz F, Femino EL, Gonzalez AL, Coutinho L, Butcher D, Edmondson EF, Rangel MC, Kinders RJ, Lipkowitz S, Wong ST, Anderson SK, McVicar DW, Li X, Glynn SA, Billiar TR, Chang JC, Hewitt SM, Ambs S, Lockett SJ, Wink DA. Ridnour LA, et al. Among authors: chang jc. bioRxiv [Preprint]. 2023 Dec 23:2023.12.21.572859. doi: 10.1101/2023.12.21.572859. bioRxiv. 2023. PMID: 38187532 Free PMC article. Preprint.
Adjuvant COX inhibition augments STING signaling and cytolytic T cell infiltration in irradiated 4T1 tumors.
Ridnour LA, Cheng RY, Kedei N, Somasundaram V, Bhattacharyya DD, Basudhar D, Wink AL, Walke AJ, Kim C, Heinz WF, Edmondson EF, Butcher DO, Warner AC, Dorsey TH, Pore M, Kinders RJ, Lipkowitz S, Bryant RJ, Rittscher J, Wong ST, Hewitt SM, Chang JC, Shalaby A, Callagy GM, Glynn SA, Ambs S, Anderson SK, McVicar DW, Lockett SJ, Wink DA. Ridnour LA, et al. Among authors: chang jc. JCI Insight. 2024 May 21;9(12):e165356. doi: 10.1172/jci.insight.165356. JCI Insight. 2024. PMID: 38912586 Free PMC article.
Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome.
Thomas D, Palczewski M, Kuschman H, Hoffman B, Yang H, Glynn S, Wilson D, Kool E, Montfort W, Chang J, Petenkaya A, Chronis C, Cundari T, Sappa S, Islam K, McVicar D, Fan Y, Chen Q, Meerzaman D, Sierk M. Thomas D, et al. Res Sq [Preprint]. 2024 Apr 3:rs.3.rs-4131804. doi: 10.21203/rs.3.rs-4131804/v1. Res Sq. 2024. PMID: 38645113 Free PMC article. Preprint.
Astrocyte-derived extracellular matrix proteins regulate synapse remodeling in stress-induced depression.
Zhang R, Rodriguez-Rodriguez P, Medrihan L, Chang JC, Ferraro T, Del Cioppo Vasques P, Wang W, Menard C, Cathomas F, Chan KL, Parise L, Shaham S, Roussarie JP, Troyanskaya O, Russo SJ, Milosevic A. Zhang R, et al. Among authors: chang jc. bioRxiv [Preprint]. 2024 Dec 30:2024.12.30.630684. doi: 10.1101/2024.12.30.630684. bioRxiv. 2024. PMID: 39803419 Free PMC article. Preprint.
Erinacine A-Enriched Hericium erinaceus Mycelium Ethanol Extract Lessens Cellular Damage in Cell and Drosophila Models of Spinocerebellar Ataxia Type 3 by Improvement of Nrf2 Activation.
Wu YL, Sun HL, Chang JC, Lin WY, Chen PY, Chen CC, Lee LY, Li CC, Hsieh M, Chen HW, Yang YC, Liu CS, Liu KL. Wu YL, et al. Among authors: chang jc. Antioxidants (Basel). 2024 Dec 7;13(12):1495. doi: 10.3390/antiox13121495. Antioxidants (Basel). 2024. PMID: 39765823 Free PMC article.
1,303 results