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TGM6, a helminth secretory product, mimics TGF-β binding to TβRII to antagonize TGF-β signaling in fibroblasts.
White SE, Schwartze TA, Mukundan A, Schoenherr C, Singh SP, van Dinther M, Cunningham KT, White MPJ, Campion T, Pritchard J, Hinck CS, Ten Dijke P, Inman G, Maizels RM, Hinck AP. White SE, et al. Among authors: pritchard j. bioRxiv [Preprint]. 2023 Dec 23:2023.12.22.573140. doi: 10.1101/2023.12.22.573140. bioRxiv. 2023. PMID: 38187573 Free PMC article. Preprint.
Chromatin conformation, gene transcription, and nucleosome remodeling as an emergent system.
Almassalha LM, Carignano M, Liwag EP, Li WS, Gong R, Acosta N, Dunton CL, Gonzalez PC, Carter LM, Kakkaramadam R, Kröger M, MacQuarrie KL, Frederick J, Ye IC, Su P, Kuo T, Medina KI, Pritchard JA, Skol A, Nap R, Kanemaki M, Dravid V, Szleifer I, Backman V. Almassalha LM, et al. Among authors: pritchard ja. Sci Adv. 2025 Jan 10;11(2):eadq6652. doi: 10.1126/sciadv.adq6652. Epub 2025 Jan 10. Sci Adv. 2025. PMID: 39792661
Docking and structure activity relationship studies of potent and selective thiazolidinethione GSK-3 inhibitors.
Boesger H, Williams K, Abdullai SA, Hubble B, Noori MS, Orac C, Amesaki DK, Ghazanfari D, Fairchild EA, Fatunbi OO, Pritchard JA, Goetz DJ, Hines JV, Bergmeier SC. Boesger H, et al. Among authors: pritchard ja. Bioorg Med Chem Lett. 2024 Dec 16;117:130074. doi: 10.1016/j.bmcl.2024.130074. Online ahead of print. Bioorg Med Chem Lett. 2024. PMID: 39694339
Central control of dynamic gene circuits governs T cell rest and activation.
Arce MM, Umhoefer JM, Arang N, Kasinathan S, Freimer JW, Steinhart Z, Shen H, Pham MTN, Ota M, Wadhera A, Dajani R, Dorovskyi D, Chen YY, Liu Q, Zhou Y, Swaney DL, Obernier K, Shy BR, Carnevale J, Satpathy AT, Krogan NJ, Pritchard JK, Marson A. Arce MM, et al. Among authors: pritchard jk. Nature. 2024 Dec 11. doi: 10.1038/s41586-024-08314-y. Online ahead of print. Nature. 2024. PMID: 39663454
1,357 results