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TGM6, a helminth secretory product, mimics TGF-β binding to TβRII to antagonize TGF-β signaling in fibroblasts.
White SE, Schwartze TA, Mukundan A, Schoenherr C, Singh SP, van Dinther M, Cunningham KT, White MPJ, Campion T, Pritchard J, Hinck CS, Ten Dijke P, Inman G, Maizels RM, Hinck AP. White SE, et al. Among authors: cunningham kt. bioRxiv [Preprint]. 2023 Dec 23:2023.12.22.573140. doi: 10.1101/2023.12.22.573140. bioRxiv. 2023. PMID: 38187573 Free PMC article. Preprint.
The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding.
Singh SP, Smyth DJ, Cunningham KT, Mukundan A, Byeon CH, Hinck CS, White MPJ, Ciancia C, Wąsowska N, Sanders A, Jin R, White RF, Lilla S, Zanivan S, Schoenherr C, Inman GJ, van Dinther M, Ten Dijke P, Hinck AP, Maizels RM. Singh SP, et al. Among authors: cunningham kt. EMBO Rep. 2024 Nov 28. doi: 10.1038/s44319-024-00323-2. Online ahead of print. EMBO Rep. 2024. PMID: 39609640 Free article.
We are what we eat: macrophages and efferocytosis.
Cunningham KT, Maizels RM. Cunningham KT, et al. Trends Parasitol. 2024 Jun;40(6):446-448. doi: 10.1016/j.pt.2024.05.004. Epub 2024 May 20. Trends Parasitol. 2024. PMID: 38772757 Free article.
CD44 acts as a coreceptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic.
van Dinther M, Cunningham KT, Singh SP, White MPJ, Campion T, Ciancia C, van Veelen PA, de Ru AH, González-Prieto R, Mukundan A, Byeon CH, Staggers SR, Hinck CS, Hinck AP, Dijke PT, Maizels RM. van Dinther M, et al. Among authors: cunningham kt. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2302370120. doi: 10.1073/pnas.2302370120. Epub 2023 Aug 17. Proc Natl Acad Sci U S A. 2023. PMID: 37590410 Free PMC article.
19 results