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Human alveolar lining fluid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells.
Olmo-Fontánez AM, Scordo JM, Schami A, Garcia-Vilanova A, Pino PA, Hicks A, Mishra R, Jose Maselli D, Peters JI, Restrepo BI, Nargan K, Naidoo T, Clemens DL, Steyn AJC, Thacker VV, Turner J, Schlesinger LS, Torrelles JB. Olmo-Fontánez AM, et al. Among authors: steyn ajc. Mucosal Immunol. 2024 Apr;17(2):155-168. doi: 10.1016/j.mucimm.2024.01.001. Epub 2024 Jan 6. Mucosal Immunol. 2024. PMID: 38185331 Free PMC article.
Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection.
Reddy VP, Chinta KC, Saini V, Glasgow JN, Hull TD, Traylor A, Rey-Stolle F, Soares MP, Madansein R, Rahman MA, Barbas C, Nargan K, Naidoo T, Ramdial PK, George JF, Agarwal A, Steyn AJC. Reddy VP, et al. Among authors: steyn ajc. Front Immunol. 2018 May 3;9:860. doi: 10.3389/fimmu.2018.00860. eCollection 2018. Front Immunol. 2018. PMID: 29774023 Free PMC article.
Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis.
Chinta KC, Rahman MA, Saini V, Glasgow JN, Reddy VP, Lever JM, Nhamoyebonde S, Leslie A, Wells RM, Traylor A, Madansein R, Siegal GP, Antony VB, Deshane J, Wells G, Nargan K, George JF, Ramdial PK, Agarwal A, Steyn AJC. Chinta KC, et al. Among authors: steyn ajc. Cell Rep. 2018 Nov 13;25(7):1938-1952.e5. doi: 10.1016/j.celrep.2018.10.073. Cell Rep. 2018. PMID: 30428359 Free PMC article.
Micro-Computed Tomography Analysis of the Human Tuberculous Lung Reveals Remarkable Heterogeneity in Three-dimensional Granuloma Morphology.
Wells G, Glasgow JN, Nargan K, Lumamba K, Madansein R, Maharaj K, Hunter RL, Naidoo T, Coetzer L, le Roux S, du Plessis A, Steyn AJC. Wells G, et al. Among authors: steyn ajc. Am J Respir Crit Care Med. 2021 Sep 1;204(5):583-595. doi: 10.1164/rccm.202101-0032OC. Am J Respir Crit Care Med. 2021. PMID: 34015247 Free PMC article.
Aggregated Mycobacterium tuberculosis Enhances the Inflammatory Response.
Rodel HE, Ferreira IATM, Ziegler CGK, Ganga Y, Bernstein M, Hwa SH, Nargan K, Lustig G, Kaplan G, Noursadeghi M, Shalek AK, Steyn AJC, Sigal A. Rodel HE, et al. Among authors: steyn ajc. Front Microbiol. 2021 Dec 2;12:757134. doi: 10.3389/fmicb.2021.757134. eCollection 2021. Front Microbiol. 2021. PMID: 34925266 Free PMC article.
A high-resolution 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions.
Wells G, Glasgow JN, Nargan K, Lumamba K, Madansein R, Maharaj K, Perumal LY, Matthew M, Hunter RL, Pacl H, Peabody Lever JE, Stanford DD, Singh SP, Bajpai P, Manne U, Benson PV, Rowe SM, le Roux S, Sigal A, Tshibalanganda M, Wells C, du Plessis A, Msimang M, Naidoo T, Steyn AJC. Wells G, et al. Among authors: steyn ajc. EMBO Mol Med. 2022 Nov 8;14(11):e16283. doi: 10.15252/emmm.202216283. Epub 2022 Oct 26. EMBO Mol Med. 2022. PMID: 36285507 Free PMC article.
97 results