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Camptothecin structure simplification elaborated new imidazo[2,1-b]quinazoline derivative as a human topoisomerase I inhibitor with efficacy against bone cancer cells and colon adenocarcinoma.
Khodair AI, El-Hallouty SM, Cagle-White B, Abdel Aziz MH, Hanafy MK, Mowafy S, Hamdy NM, Kassab SE. Khodair AI, et al. Among authors: hanafy mk. Eur J Med Chem. 2024 Feb 5;265:116049. doi: 10.1016/j.ejmech.2023.116049. Epub 2023 Dec 16. Eur J Med Chem. 2024. PMID: 38185054