Smith RL - Search Results

1

Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study.

Koch E, Kämpe A, Alver M, Sigurðarson S, Einarsson G, Partanen J, Smith RL, Jaholkowski P, Taipale H, Lähteenvuo M, Steen NE, Smeland OB, Djurovic S, Molden E; FinnGen; Estonian Biobank Research Team; Sigurdsson E, Stefánsson H, Stefánsson K, Palotie A, Milani L, O'Connell KS, Andreassen OA. Koch E, et al. Among authors: smith rl. Neuropsychopharmacology. 2024 Jun;49(7):1113-1119. doi: 10.1038/s41386-023-01792-0. Epub 2024 Jan 6. Neuropsychopharmacology. 2024. PMID: 38184734

2

Impact of age, gender and CYP2C9/2C19 genotypes on dose-adjusted steady-state serum concentrations of valproic acid-a large-scale study based on naturalistic therapeutic drug monitoring data.

Smith RL, Haslemo T, Refsum H, Molden E. Smith RL, et al. Eur J Clin Pharmacol. 2016 Sep;72(9):1099-104. doi: 10.1007/s00228-016-2087-0. Epub 2016 Jun 29. Eur J Clin Pharmacol. 2016. PMID: 27353638

3

Correlation Between Serum Concentrations of N-Desmethylclozapine and Granulocyte Levels in Patients with Schizophrenia: A Retrospective Observational Study.

Smith RL, Haslemo T, Andreassen OA, Eliasson E, Dahl ML, Spigset O, Molden E. Smith RL, et al. CNS Drugs. 2017 Nov;31(11):991-997. doi: 10.1007/s40263-017-0469-1. CNS Drugs. 2017. PMID: 28948574

4

Clinically Relevant Effect of UGT1A4*3 on Lamotrigine Serum Concentration Is Restricted to Postmenopausal Women-A Study Matching Therapeutic Drug Monitoring and Genotype Data From 534 Patients.

Smith RL, Haslemo T, Chan HF, Refsum H, Molden E. Smith RL, et al. Ther Drug Monit. 2018 Oct;40(5):567-571. doi: 10.1097/FTD.0000000000000540. Ther Drug Monit. 2018. PMID: 30086088

5

Age Impacts Olanzapine Exposure Differently During Use of Oral Versus Long-Acting Injectable Formulations: An Observational Study Including 8,288 Patients.

Tveito M, Smith RL, Molden E, Haslemo T, Refsum H, Hartberg C, Correll CU, Høiseth G. Tveito M, et al. Among authors: smith rl. J Clin Psychopharmacol. 2018 Dec;38(6):570-576. doi: 10.1097/JCP.0000000000000961. J Clin Psychopharmacol. 2018. PMID: 30300295

6

Effect of CYP2D6 genotype on exposure and efficacy of risperidone and aripiprazole: a retrospective, cohort study.

Jukic MM, Smith RL, Haslemo T, Molden E, Ingelman-Sundberg M. Jukic MM, et al. Among authors: smith rl. Lancet Psychiatry. 2019 May;6(5):418-426. doi: 10.1016/S2215-0366(19)30088-4. Epub 2019 Apr 15. Lancet Psychiatry. 2019. PMID: 31000417

7

Reduction in N-Desmethylclozapine Level Is Determined by Daily Dose But Not Serum Concentration of Valproic Acid-Indications of a Presystemic Interaction Mechanism.

Smith RL, Kyllesø L, Haslemo T, Andreassen OA, Molden E. Smith RL, et al. Ther Drug Monit. 2019 Aug;41(4):503-508. doi: 10.1097/FTD.0000000000000619. Ther Drug Monit. 2019. PMID: 31259880

8

Impact of age and CYP2D6 genetics on exposure of aripiprazole and dehydroaripiprazole in patients using long-acting injectable versus oral formulation: relevance of poor and intermediate metabolizer status.

Tveito M, Molden E, Høiseth G, Correll CU, Smith RL. Tveito M, et al. Among authors: smith rl. Eur J Clin Pharmacol. 2020 Jan;76(1):41-49. doi: 10.1007/s00228-019-02768-0. Epub 2019 Oct 21. Eur J Clin Pharmacol. 2020. PMID: 31637453

9

The Effect of Valproic Acid on Olanzapine Serum Concentration: A Study Including 2791 Patients Treated With Olanzapine Tablets or Long-Acting Injections.

Tveito M, Smith RL, Høiseth G, Molden E. Tveito M, et al. Among authors: smith rl. J Clin Psychopharmacol. 2019 Nov/Dec;39(6):561-566. doi: 10.1097/JCP.0000000000001126. J Clin Psychopharmacol. 2019. PMID: 31688390

10

Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits.

Smith RL, O'Connell K, Athanasiu L, Djurovic S, Kringen MK, Andreassen OA, Molden E. Smith RL, et al. Transl Psychiatry. 2020 Jun 19;10(1):198. doi: 10.1038/s41398-020-00888-1. Transl Psychiatry. 2020. PMID: 32555152 Free PMC article.

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