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A time- and single-cell-resolved model of murine bone marrow hematopoiesis.
Kucinski I, Campos J, Barile M, Severi F, Bohin N, Moreira PN, Allen L, Lawson H, Haltalli MLR, Kinston SJ, O'Carroll D, Kranc KR, Göttgens B. Kucinski I, et al. Among authors: gottgens b. Cell Stem Cell. 2024 Feb 1;31(2):244-259.e10. doi: 10.1016/j.stem.2023.12.001. Epub 2024 Jan 5. Cell Stem Cell. 2024. PMID: 38183977 Free PMC article.
The scl +18/19 stem cell enhancer is not required for hematopoiesis: identification of a 5' bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1.
Göttgens B, Broccardo C, Sanchez MJ, Deveaux S, Murphy G, Göthert JR, Kotsopoulou E, Kinston S, Delaney L, Piltz S, Barton LM, Knezevic K, Erber WN, Begley CG, Frampton J, Green AR. Göttgens B, et al. Mol Cell Biol. 2004 Mar;24(5):1870-83. doi: 10.1128/MCB.24.5.1870-1883.2004. Mol Cell Biol. 2004. PMID: 14966269 Free PMC article.
The paralogous hematopoietic regulators Lyl1 and Scl are coregulated by Ets and GATA factors, but Lyl1 cannot rescue the early Scl-/- phenotype.
Chan WY, Follows GA, Lacaud G, Pimanda JE, Landry JR, Kinston S, Knezevic K, Piltz S, Donaldson IJ, Gambardella L, Sablitzky F, Green AR, Kouskoff V, Göttgens B. Chan WY, et al. Among authors: gottgens b. Blood. 2007 Mar 1;109(5):1908-16. doi: 10.1182/blood-2006-05-023226. Epub 2006 Oct 19. Blood. 2007. PMID: 17053063 Free article.
Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver.
Landry JR, Kinston S, Knezevic K, de Bruijn MF, Wilson N, Nottingham WT, Peitz M, Edenhofer F, Pimanda JE, Ottersbach K, Göttgens B. Landry JR, et al. Among authors: gottgens b. Blood. 2008 Mar 15;111(6):3005-14. doi: 10.1182/blood-2007-07-098830. Epub 2008 Jan 9. Blood. 2008. PMID: 18184866 Free article.
331 results