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A time- and single-cell-resolved model of murine bone marrow hematopoiesis.
Kucinski I, Campos J, Barile M, Severi F, Bohin N, Moreira PN, Allen L, Lawson H, Haltalli MLR, Kinston SJ, O'Carroll D, Kranc KR, Göttgens B. Kucinski I, et al. Among authors: campos j. Cell Stem Cell. 2024 Feb 1;31(2):244-259.e10. doi: 10.1016/j.stem.2023.12.001. Epub 2024 Jan 5. Cell Stem Cell. 2024. PMID: 38183977 Free PMC article.
Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia.
Paris J, Morgan M, Campos J, Spencer GJ, Shmakova A, Ivanova I, Mapperley C, Lawson H, Wotherspoon DA, Sepulveda C, Vukovic M, Allen L, Sarapuu A, Tavosanis A, Guitart AV, Villacreces A, Much C, Choe J, Azar A, van de Lagemaat LN, Vernimmen D, Nehme A, Mazurier F, Somervaille TCP, Gregory RI, O'Carroll D, Kranc KR. Paris J, et al. Among authors: campos j. Cell Stem Cell. 2019 Jul 3;25(1):137-148.e6. doi: 10.1016/j.stem.2019.03.021. Epub 2019 Apr 25. Cell Stem Cell. 2019. PMID: 31031138 Free PMC article.
The mRNA m6A reader YTHDF2 suppresses proinflammatory pathways and sustains hematopoietic stem cell function.
Mapperley C, van de Lagemaat LN, Lawson H, Tavosanis A, Paris J, Campos J, Wotherspoon D, Durko J, Sarapuu A, Choe J, Ivanova I, Krause DS, von Kriegsheim A, Much C, Morgan M, Gregory RI, Mead AJ, O'Carroll D, Kranc KR. Mapperley C, et al. Among authors: campos j. J Exp Med. 2021 Mar 1;218(3):e20200829. doi: 10.1084/jem.20200829. J Exp Med. 2021. PMID: 33156926 Free PMC article.
JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells.
Lawson H, Sepulveda C, van de Lagemaat LN, Durko J, Barile M, Tavosanis A, Georges E, Shmakova A, Timms P, Carter RN, Allen L, Campos J, Vukovic M, Guitart AV, Giles P, O'Shea M, Vernimmen D, Morton NM, Rodrigues NP, Göttgens B, Schofield CJ, Lengeling A, O'Carroll D, Kranc KR. Lawson H, et al. Among authors: campos j. Blood Adv. 2021 Feb 9;5(3):889-899. doi: 10.1182/bloodadvances.2020002702. Blood Adv. 2021. PMID: 33560400 Free PMC article.
CITED2 coordinates key hematopoietic regulatory pathways to maintain the HSC pool in both steady-state hematopoiesis and transplantation.
Lawson H, van de Lagemaat LN, Barile M, Tavosanis A, Durko J, Villacreces A, Bellani A, Mapperley C, Georges E, Martins-Costa C, Sepulveda C, Allen L, Campos J, Campbell KJ, O'Carroll D, Göttgens B, Cory S, Rodrigues NP, Guitart AV, Kranc KR. Lawson H, et al. Among authors: campos j. Stem Cell Reports. 2021 Nov 9;16(11):2784-2797. doi: 10.1016/j.stemcr.2021.10.001. Epub 2021 Oct 28. Stem Cell Reports. 2021. PMID: 34715054 Free PMC article.
Stearoyl-CoA desaturase inhibition is toxic to acute myeloid leukemia displaying high levels of the de novo fatty acid biosynthesis and desaturation.
Dembitz V, Lawson H, Burt R, Natani S, Philippe C, James SC, Atkinson S, Durko J, Wang LM, Campos J, Magee AMS, Woodley K, Austin MJ, Rio-Machin A, Casado P, Bewicke-Copley F, Rodriguez Blanco G, Pereira-Martins D, Oudejans L, Boet E, von Kriegsheim A, Schwaller J, Finch AJ, Patel B, Sarry JE, Tamburini J, Schuringa JJ, Hazlehurst L, Copland Iii JA, Yuneva M, Peck B, Cutillas P, Fitzgibbon J, Rouault-Pierre K, Kranc K, Gallipoli P. Dembitz V, et al. Among authors: campos j. Leukemia. 2024 Nov;38(11):2395-2409. doi: 10.1038/s41375-024-02390-9. Epub 2024 Aug 26. Leukemia. 2024. PMID: 39187579 Free PMC article.
Engaging older adults in the process of aging research: a multimethod study evaluating the experience and efficacy of a citizen advisory group for a dementia risk reduction program.
D'Amico D, Savundranayagam MY, Biles R, Itzhak I, Anderson ND; Canadian Consortium on Neurodegeneration in Aging (CCNA) CAN-THUMBS UP Study Group. D'Amico D, et al. Res Involv Engagem. 2024 Dec 27;10(1):135. doi: 10.1186/s40900-024-00643-6. Res Involv Engagem. 2024. PMID: 39731188
2,884 results