Somani S - Search Results

1

Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing.

Matico RE, Yu X, Miller R, Somani S, Ricketts MD, Kumar N, Steele RA, Medley Q, Berger S, Faustin B, Sharma S. Matico RE, et al. Among authors: somani s. Nat Struct Mol Biol. 2024 Jan;31(1):82-91. doi: 10.1038/s41594-023-01143-z. Epub 2024 Jan 4. Nat Struct Mol Biol. 2024. PMID: 38177670 Free PMC article.

2

Residue-Specific Impact of EDTA and Methionine on Protein Oxidation in Biotherapeutics Formulations Using an Integrated Biotherapeutics Drug Product Development Workflow.

Thakkar SV, Rodrigues D, Zhai B, Banton D, Somani S, Javidi A, Mahan A, Ember S, DeGrazio D, Ganguly S, Amin K, Nanda H. Thakkar SV, et al. Among authors: somani s. J Pharm Sci. 2023 Feb;112(2):471-481. doi: 10.1016/j.xphs.2022.09.011. Epub 2022 Sep 18. J Pharm Sci. 2023. PMID: 36130676

3

Toward Biotherapeutics Formulation Composition Engineering using Site-Identification by Ligand Competitive Saturation (SILCS).

Somani S, Jo S, Thirumangalathu R, Rodrigues D, Tanenbaum LM, Amin K, MacKerell AD Jr, Thakkar SV. Somani S, et al. J Pharm Sci. 2021 Mar;110(3):1103-1110. doi: 10.1016/j.xphs.2020.10.051. Epub 2020 Nov 1. J Pharm Sci. 2021. PMID: 33137372 Free PMC article.

4

Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.

Tam SH, McCarthy SG, Armstrong AA, Somani S, Wu SJ, Liu X, Gervais A, Ernst R, Saro D, Decker R, Luo J, Gilliland GL, Chiu ML, Scallon BJ. Tam SH, et al. Among authors: somani s. Antibodies (Basel). 2017 Sep 1;6(3):12. doi: 10.3390/antib6030012. Antibodies (Basel). 2017. PMID: 31548527 Free PMC article.

5

Homology-based hydrogen bond information improves crystallographic structures in the PDB.

van Beusekom B, Touw WG, Tatineni M, Somani S, Rajagopal G, Luo J, Gilliland GL, Perrakis A, Joosten RP. van Beusekom B, et al. Among authors: somani s. Protein Sci. 2018 Mar;27(3):798-808. doi: 10.1002/pro.3353. Epub 2017 Dec 8. Protein Sci. 2018. PMID: 29168245 Free PMC article.

6

Product-Specific Impact of Viscosity Modulating Formulation Excipients During Ultra-High Concentration Biotherapeutics Drug Product Development.

Rodrigues D, Tanenbaum LM, Thirumangalathu R, Somani S, Zhang K, Kumar V, Amin K, Thakkar SV. Rodrigues D, et al. Among authors: somani s. J Pharm Sci. 2021 Mar;110(3):1077-1082. doi: 10.1016/j.xphs.2020.12.016. Epub 2020 Dec 17. J Pharm Sci. 2021. PMID: 33340533

7

Configurational entropy in protein-peptide binding: computational study of Tsg101 ubiquitin E2 variant domain with an HIV-derived PTAP nonapeptide.

Killian BJ, Kravitz JY, Somani S, Dasgupta P, Pang YP, Gilson MK. Killian BJ, et al. Among authors: somani s. J Mol Biol. 2009 Jun 5;389(2):315-35. doi: 10.1016/j.jmb.2009.04.003. Epub 2009 Apr 9. J Mol Biol. 2009. PMID: 19362095 Free PMC article.

8

Computational Characterization of Antibody-Excipient Interactions for Rational Excipient Selection Using the Site Identification by Ligand Competitive Saturation-Biologics Approach.

Jo S, Xu A, Curtis JE, Somani S, MacKerell AD Jr. Jo S, et al. Among authors: somani s. Mol Pharm. 2020 Nov 2;17(11):4323-4333. doi: 10.1021/acs.molpharmaceut.0c00775. Epub 2020 Oct 6. Mol Pharm. 2020. PMID: 32965126 Free PMC article.

9

Comparison of HEmorrhage on CT versus MRI After ThrombEctomy: The HECATE study.

Hsia AW, Latour LL, Somani S, Lomahan CA, Kim Y, Lynch JK, Luby M. Hsia AW, et al. Among authors: somani s. Stroke Vasc Interv Neurol. 2024 Nov;4(6):e001441. Epub 2024 Aug 30. Stroke Vasc Interv Neurol. 2024. PMID: 39668975

10

A mixed-methods exploration of the Real-Time Virtual Support pathway Child Health Advice in Real-Time Electronically in Northwestern BC.

Duke S, Treissman J, Freeman S, Rossnagel E, Somani S, Lakhani A, Miller K, Pawlovich J, Wensley D. Duke S, et al. Among authors: somani s. Paediatr Child Health. 2024 Oct 10;29(6):346-353. doi: 10.1093/pch/pxae063. eCollection 2024 Sep. Paediatr Child Health. 2024. PMID: 39539777 Free PMC article.

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