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Versican accumulation drives Nos2 induction and aortic disease in Marfan syndrome via Akt activation.
Ruiz-Rodríguez MJ, Oller J, Martínez-Martínez S, Alarcón-Ruiz I, Toral M, Sun Y, Colmenar Á, Méndez-Olivares MJ, López-Maderuelo D, Kern CB, Nistal JF, Evangelista A, Teixido-Tura G, Campanero MR, Redondo JM. Ruiz-Rodríguez MJ, et al. Among authors: nistal jf. EMBO Mol Med. 2024 Jan;16(1):132-157. doi: 10.1038/s44321-023-00009-7. Epub 2024 Jan 2. EMBO Mol Med. 2024. PMID: 38177536 Free PMC article.
Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome.
Oller J, Méndez-Barbero N, Ruiz EJ, Villahoz S, Renard M, Canelas LI, Briones AM, Alberca R, Lozano-Vidal N, Hurlé MA, Milewicz D, Evangelista A, Salaices M, Nistal JF, Jiménez-Borreguero LJ, De Backer J, Campanero MR, Redondo JM. Oller J, et al. Among authors: nistal jf. Nat Med. 2017 Feb;23(2):200-212. doi: 10.1038/nm.4266. Epub 2017 Jan 9. Nat Med. 2017. PMID: 28067899
Extracellular Tuning of Mitochondrial Respiration Leads to Aortic Aneurysm.
Oller J, Gabandé-Rodríguez E, Ruiz-Rodríguez MJ, Desdín-Micó G, Aranda JF, Rodrigues-Diez R, Ballesteros-Martínez C, Blanco EM, Roldan-Montero R, Acuña P, Forteza Gil A, Martín-López CE, Nistal JF, Lino Cardenas CL, Lindsay ME, Martín-Ventura JL, Briones AM, Redondo JM, Mittelbrunn M. Oller J, et al. Among authors: nistal jf. Circulation. 2021 May 25;143(21):2091-2109. doi: 10.1161/CIRCULATIONAHA.120.051171. Epub 2021 Mar 12. Circulation. 2021. PMID: 33709773 Free PMC article.
Aortic disease in Marfan syndrome is caused by overactivation of sGC-PRKG signaling by NO.
de la Fuente-Alonso A, Toral M, Alfayate A, Ruiz-Rodríguez MJ, Bonzón-Kulichenko E, Teixido-Tura G, Martínez-Martínez S, Méndez-Olivares MJ, López-Maderuelo D, González-Valdés I, Garcia-Izquierdo E, Mingo S, Martín CE, Muiño-Mosquera L, De Backer J, Nistal JF, Forteza A, Evangelista A, Vázquez J, Campanero MR, Redondo JM. de la Fuente-Alonso A, et al. Among authors: nistal jf. Nat Commun. 2021 May 11;12(1):2628. doi: 10.1038/s41467-021-22933-3. Nat Commun. 2021. PMID: 33976159 Free PMC article.
Sirtuins: To Be or Not To Be in Diabetic Cardiomyopathy.
Palomer X, Aguilar-Recarte D, García R, Nistal JF, Vázquez-Carrera M. Palomer X, et al. Among authors: nistal jf. Trends Mol Med. 2021 Jun;27(6):554-571. doi: 10.1016/j.molmed.2021.03.004. Epub 2021 Apr 7. Trends Mol Med. 2021. PMID: 33839024 Review.
BAMBI (BMP and activin membrane-bound inhibitor) protects the murine heart from pressure-overload biomechanical stress by restraining TGF-β signaling.
Villar AV, García R, Llano M, Cobo M, Merino D, Lantero A, Tramullas M, Hurlé JM, Hurlé MA, Nistal JF. Villar AV, et al. Among authors: nistal jf. Biochim Biophys Acta. 2013 Feb;1832(2):323-35. doi: 10.1016/j.bbadis.2012.11.007. Epub 2012 Nov 17. Biochim Biophys Acta. 2013. PMID: 23168040 Free article.
50 results