Paraoxonase 1 Q192R genotype and activity affect homocysteine thiolactone levels in humans.
Perła-Kaján J, Borowczyk K, Głowacki R, Nygård O, Jakubowski H.
Perła-Kaján J, et al. Among authors: glowacki r.
FASEB J. 2018 May 21:fj201800346R. doi: 10.1096/fj.201800346R. Online ahead of print.
FASEB J. 2018.
PMID: 29782204
Taken together, these findings suggest that PON1 hydrolyzes Hcy-thiolactone in humans and that the interindividual variations in PON1 genotype/activity can modulate the pathology of hyperhomocysteinemia.-Perla-Kajan, J., Borowczyk, K., Glowacki, R., Nygard, O., Jaku …
Taken together, these findings suggest that PON1 hydrolyzes Hcy-thiolactone in humans and that the interindividual variations in PON1 genoty …