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Combinatory EHMT and PARP inhibition induces an interferon response and a CD8 T cell-dependent tumor regression in PARP inhibitor-resistant models.
Nguyen LL, Watson ZL, Ortega R, Woodruff ER, Jordan KR, Iwanaga R, Yamamoto TM, Bailey CA, Jeong AD, Guntupalli SR, Behbakht K, Gbaja V, Arnoult N, Chuong EB, Bitler BG. Nguyen LL, et al. Among authors: bitler bg. bioRxiv [Preprint]. 2023 Feb 23:2023.02.23.529773. doi: 10.1101/2023.02.23.529773. bioRxiv. 2023. PMID: 36865165 Free PMC article. Preprint.
The spatial structure of the tumor immune microenvironment can explain and predict patient response in high-grade serous carcinoma.
Van Kleunen L, Ahmadian M, Post MD, Wolsky RJ, Rickert C, Jordan K, Hu J, Richer JK, Marjon NA, Behbakht K, Sikora MJ, Bitler BG, Clauset A. Van Kleunen L, et al. Among authors: bitler bg. bioRxiv [Preprint]. 2024 Jan 29:2024.01.26.577350. doi: 10.1101/2024.01.26.577350. bioRxiv. 2024. Update in: Cancer Immunol Res. 2024 Nov 4;12(11):1492-1507. doi: 10.1158/2326-6066.CIR-23-1109 PMID: 38352574 Free PMC article. Updated. Preprint.
Regulation of human interferon signaling by transposon exonization.
Pasquesi GIM, Allen H, Ivancevic A, Barbachano-Guerrero A, Joyner O, Guo K, Simpson DM, Gapin K, Horton I, Nguyen LL, Yang Q, Warren CJ, Florea LD, Bitler BG, Santiago ML, Sawyer SL, Chuong EB. Pasquesi GIM, et al. Among authors: bitler bg. Cell. 2024 Dec 26;187(26):7621-7636.e19. doi: 10.1016/j.cell.2024.11.016. Epub 2024 Dec 12. Cell. 2024. PMID: 39672162 Free article.
99 results