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Modulation of tumor microenvironment by targeting histone acetylation in bladder cancer.
Nunes SP, Morales L, Rubio C, Munera-Maravilla E, Lodewijk I, Suárez-Cabrera C, Martínez VG, Pérez-Escavy M, Pérez-Crespo M, Alonso Sánchez M, Montesinos E, San José-Enériz E, Agirre X, Prósper F, Pineda-Lucena A, Henrique R, Dueñas M, Correia MP, Jerónimo C, Paramio JM. Nunes SP, et al. Among authors: pineda lucena a. Cell Death Discov. 2024 Jan 4;10(1):1. doi: 10.1038/s41420-023-01786-3. Cell Death Discov. 2024. PMID: 38172127 Free PMC article.
HDACi vorinostat protects muscle from degeneration after acute rotator cuff injury in mice.
Gil-Melgosa L, Llombart-Blanco R, Extramiana L, Lacave I, Abizanda G, Miranda E, Agirre X, Prósper F, Pineda-Lucena A, Pons-Villanueva J, Pérez-Ruiz A. Gil-Melgosa L, et al. Among authors: pineda lucena a. Bone Joint Res. 2024 Apr 15;13(4):169-183. doi: 10.1302/2046-3758.134.BJR-2023-0292.R1. Bone Joint Res. 2024. PMID: 38618868 Free PMC article.
Epigenetic-based differentiation therapy for Acute Myeloid Leukemia.
San José-Enériz E, Gimenez-Camino N, Rabal O, Garate L, Miranda E, Gómez-Echarte N, García F, Charalampopoulou S, Sáez E, Vilas-Zornoza A, San Martín-Uriz P, Valcárcel LV, Barrena N, Alignani D, Tamariz-Amador LE, Pérez-Ruiz A, Hilscher S, Schutkowski M, Alfonso-Pierola A, Martinez-Calle N, Larrayoz MJ, Paiva B, Calasanz MJ, Muñoz J, Isasa M, Martin-Subero JI, Pineda-Lucena A, Oyarzabal J, Agirre X, Prósper F. San José-Enériz E, et al. Among authors: pineda lucena a. Nat Commun. 2024 Jul 2;15(1):5570. doi: 10.1038/s41467-024-49784-y. Nat Commun. 2024. PMID: 38956053 Free PMC article.
An automated network-based tool to search for metabolic vulnerabilities in cancer.
Valcárcel LV, San José-Enériz E, Ordoñez R, Apaolaza I, Olaverri-Mendizabal D, Barrena N, Valcárcel A, Garate L, San Miguel J, Pineda-Lucena A, Agirre X, Prósper F, Planes FJ. Valcárcel LV, et al. Among authors: pineda lucena a. Nat Commun. 2024 Oct 11;15(1):8685. doi: 10.1038/s41467-024-52725-4. Nat Commun. 2024. PMID: 39394196 Free PMC article.
G9a/DNMT1 co-targeting inhibits non-small cell lung cancer growth and reprograms tumor cells to respond to cancer-drugs through SCARA5 and AOX1.
Exposito F, Redrado M, Serrano D, Calabuig-Fariñas S, Bao-Caamano A, Gallach S, Jantus-Lewintre E, Diaz-Lagares A, Rodriguez-Casanova A, Sandoval J, San Jose-Eneriz E, Garcia J, Redin E, Senent Y, Leon S, Pio R, Lopez R, Oyarzabal J, Pineda-Lucena A, Agirre X, Montuenga LM, Prosper F, Calvo A. Exposito F, et al. Among authors: pineda lucena a. Cell Death Dis. 2024 Nov 2;15(11):787. doi: 10.1038/s41419-024-07156-w. Cell Death Dis. 2024. PMID: 39488528 Free PMC article.
Identification and experimental validation of druggable epigenetic targets in hepatoblastoma.
Clavería-Cabello A, Herranz JM, Latasa MU, Arechederra M, Uriarte I, Pineda-Lucena A, Prosper F, Berraondo P, Alonso C, Sangro B, García Marin JJ, Martinez-Chantar ML, Ciordia S, Corrales FJ, Francalanci P, Alaggio R, Zucman-Rossi J, Indersie E, Cairo S, Domingo-Sàbat M, Zanatto L, Sancho-Bru P, Armengol C, Berasain C, Fernandez-Barrena MG, Avila MA. Clavería-Cabello A, et al. J Hepatol. 2023 Oct;79(4):989-1005. doi: 10.1016/j.jhep.2023.05.031. Epub 2023 Jun 10. J Hepatol. 2023. PMID: 37302584 Free article.
AG5 is a potent non-steroidal anti-inflammatory and immune regulator that preserves innate immunity.
Botella-Asunción P, Rivero-Buceta EM, Vidaurre-Agut C, Lama R, Rey-Campos M, Moreno A, Mendoza L, Mingo-Casas P, Escribano-Romero E, Gutierrez-Adan A, Saiz JC, Smerdou C, Gonzalez G, Prosper F, Argemí J, Miguel JS, Sanchez-Cordón PJ, Figueras A, Quesada-Gomez JM, Novoa B, Montoya M, Martín-Acebes MA, Pineda-Lucena A, Benlloch JM. Botella-Asunción P, et al. Biomed Pharmacother. 2023 Dec 31;169:115882. doi: 10.1016/j.biopha.2023.115882. Epub 2023 Nov 18. Biomed Pharmacother. 2023. PMID: 37984300 Free article.
Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer.
Macaya I, Roman M, Welch C, Entrialgo-Cadierno R, Salmon M, Santos A, Feliu I, Kovalski J, Lopez I, Rodriguez-Remirez M, Palomino-Echeverria S, Lonfgren SM, Ferrero M, Calabuig S, Ludwig IA, Lara-Astiaso D, Jantus-Lewintre E, Guruceaga E, Narayanan S, Ponz-Sarvise M, Pineda-Lucena A, Lecanda F, Ruggero D, Khatri P, Santamaria E, Fernandez-Irigoyen J, Ferrer I, Paz-Ares L, Drosten M, Barbacid M, Gil-Bazo I, Vicent S. Macaya I, et al. Nat Commun. 2023 Oct 10;14(1):6332. doi: 10.1038/s41467-023-41828-z. Nat Commun. 2023. PMID: 37816716 Free PMC article.
Protein Biomarkers in Lung Cancer Screening: Technical Considerations and Feasibility Assessment.
Orive D, Echepare M, Bernasconi-Bisio F, Sanmamed MF, Pineda-Lucena A, de la Calle-Arroyo C, Detterbeck F, Hung RJ, Johansson M, Robbins HA, Seijo LM, Montuenga LM, Valencia K. Orive D, et al. Among authors: pineda lucena a. Arch Bronconeumol. 2024 Oct;60 Suppl 2:S67-S76. doi: 10.1016/j.arbres.2024.07.007. Epub 2024 Jul 17. Arch Bronconeumol. 2024. PMID: 39079848 Free article. Review. English, Spanish.
140 results