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New insights in the mechanism of the SARS-CoV-2 Mpro inhibition by benzisoselenazolones and diselenides.
Sancineto L, Mangiavacchi F, Dabrowska A, Pacuła-Miszewska AJ, Obieziurska-Fabisiak M, Scimmi C, Ceccucci V, Kong J, Zhao Y, Ciancaleoni G, Nascimento V, Rizzuti B, Bortoli M, Orian L, Kula-Pacurar A, Yang H, Ścianowski J, Lei Y, Pyrc K, Santi C. Sancineto L, et al. Among authors: kula pacurar a. Sci Rep. 2024 Oct 21;14(1):24751. doi: 10.1038/s41598-024-75519-6. Sci Rep. 2024. PMID: 39433805 Free PMC article.
Ceragenins exhibit antiviral activity against SARS-CoV-2 by increasing the expression and release of type I interferons upon activation of the host's immune response.
Suprewicz Ł, Szczepański A, Lenart M, Piktel E, Fiedoruk K, Barreto-Duran E, Kula-Pacurar A, Savage PB, Milewska A, Bucki R, Pyrć K. Suprewicz Ł, et al. Among authors: kula pacurar a. Antiviral Res. 2023 Sep;217:105676. doi: 10.1016/j.antiviral.2023.105676. Epub 2023 Jul 20. Antiviral Res. 2023. PMID: 37481038
Chalcogenium-AZT Derivatives: A Plausible Strategy To Tackle The RT-Inhibitors-Related Oxidative Stress While Maintaining Their Anti- HIV Properties.
Sarturi JM, Dornelles L, Segatto NV, Collares T, Seixas FK, Piccoli BC, da Silva FD, Omage FB, da Rocha JBT, Balaguez RA, Alves D, Lenardão EJ, Lopes EF, Kula-Pacurar A, Pyrc K, Sancineto L, Rodrigues OED. Sarturi JM, et al. Among authors: kula pacurar a. Curr Med Chem. 2023;30(21):2449-2462. doi: 10.2174/0929867329666220906095438. Curr Med Chem. 2023. PMID: 36065927
l-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells.
Sancineto L, Ostacolo C, Ortega-Alarcon D, Jimenez-Alesanco A, Ceballos-Laita L, Vega S, Abian O, Velazquez-Campoy A, Moretti S, Dabrowska A, Botwina P, Synowiec A, Kula-Pacurar A, Pyrc K, Iraci N, Santi C. Sancineto L, et al. Among authors: kula pacurar a. Molecules. 2021 Oct 7;26(19):6062. doi: 10.3390/molecules26196062. Molecules. 2021. PMID: 34641606 Free PMC article.
Seleno-Functionalization of Quercetin Improves the Non-Covalent Inhibition of Mpro and Its Antiviral Activity in Cells against SARS-CoV-2.
Mangiavacchi F, Botwina P, Menichetti E, Bagnoli L, Rosati O, Marini F, Fonseca SF, Abenante L, Alves D, Dabrowska A, Kula-Pacurar A, Ortega-Alarcon D, Jimenez-Alesanco A, Ceballos-Laita L, Vega S, Rizzuti B, Abian O, Lenardão EJ, Velazquez-Campoy A, Pyrc K, Sancineto L, Santi C. Mangiavacchi F, et al. Among authors: kula pacurar a. Int J Mol Sci. 2021 Jun 30;22(13):7048. doi: 10.3390/ijms22137048. Int J Mol Sci. 2021. PMID: 34208928 Free PMC article.
Shocking HIV-1 with immunomodulatory latency reversing agents.
Kula-Pacurar A, Rodari A, Darcis G, Van Lint C. Kula-Pacurar A, et al. Semin Immunol. 2021 Jan;51:101478. doi: 10.1016/j.smim.2021.101478. Epub 2021 May 8. Semin Immunol. 2021. PMID: 33972164 Free article. Review.
12 results