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Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections.
Konstantinović J, Kany AM, Alhayek A, Abdelsamie AS, Sikandar A, Voos K, Yao Y, Andreas A, Shafiei R, Loretz B, Schönauer E, Bals R, Brandstetter H, Hartmann RW, Ducho C, Lehr CM, Beisswenger C, Müller R, Rox K, Haupenthal J, Hirsch AKH. Konstantinović J, et al. Among authors: shafiei r. ACS Cent Sci. 2023 Oct 27;9(12):2205-2215. doi: 10.1021/acscentsci.3c01102. eCollection 2023 Dec 27. ACS Cent Sci. 2023. PMID: 38161367 Free PMC article.
Inhibition of Collagenase Q1 of Bacillus cereus as a Novel Antivirulence Strategy for the Treatment of Skin-Wound Infections.
Alhayek A, Khan ES, Schönauer E, Däinghaus T, Shafiei R, Voos K, Han MKL, Ducho C, Posselt G, Wessler S, Brandstetter H, Haupenthal J, Del Campo A, Hirsch AKH. Alhayek A, et al. Among authors: shafiei r. Adv Ther (Weinh). 2022 Mar;5(3):2100222. doi: 10.1002/adtp.202100222. Epub 2022 Jan 15. Adv Ther (Weinh). 2022. PMID: 35310821 Free PMC article.
Structure-Based Design of α-Substituted Mercaptoacetamides as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa.
Kaya C, Walter I, Alhayek A, Shafiei R, Jézéquel G, Andreas A, Konstantinović J, Schönauer E, Sikandar A, Haupenthal J, Müller R, Brandstetter H, Hartmann RW, Hirsch AKH. Kaya C, et al. Among authors: shafiei r. ACS Infect Dis. 2022 May 13;8(5):1010-1021. doi: 10.1021/acsinfecdis.1c00628. Epub 2022 Apr 22. ACS Infect Dis. 2022. PMID: 35451824 Free PMC article.
Dual inhibitors of Pseudomonas aeruginosa virulence factors LecA and LasB.
Metelkina O, Konstantinović J, Klein A, Shafiei R, Fares M, Alhayek A, Yahiaoui S, Elgaher WAM, Haupenthal J, Titz A, Hirsch AKH. Metelkina O, et al. Among authors: shafiei r. Chem Sci. 2024 Jul 22;15(33):13333-13342. doi: 10.1039/d4sc02703e. eCollection 2024 Aug 22. Chem Sci. 2024. PMID: 39183927 Free PMC article.
73 results