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N'-Phenylacetohydrazide Derivatives as Potent Ebola Virus Entry Inhibitors with an Improved Pharmacokinetic Profile.
Garcia-Rubia A, Lasala F, Ginex T, Morales-Tenorio M, Olal C, Heung M, Oquist P, Galindo I, Cuesta-Geijo MÁ, Casasnovas JM, Campillo NE, Canales Á, Alonso C, Martínez A, Muñoz-Fontela C, Delgado R, Gil C. Garcia-Rubia A, et al. Among authors: casasnovas jm. J Med Chem. 2023 Apr 27;66(8):5465-5483. doi: 10.1021/acs.jmedchem.2c01785. Epub 2023 Apr 6. J Med Chem. 2023. PMID: 37021830 Free PMC article.
Heterologous mRNA/MVA delivering trimeric-RBD as effective vaccination regimen against SARS-CoV-2: COVARNA Consortium.
Marcos-Villar L, Perdiguero B, López-Bravo M, Zamora C, Sin L, Álvarez E, Sorzano CÓS, Sánchez-Cordón PJ, Casasnovas JM, Astorgano D, García-Arriaza J, Anthiya S, Borrajo ML, Lou G, Cuesta B, Franceschini L, Gelpí JL, Thielemans K, Sisteré-Oró M, Meyerhans A, García F, Esteban I, López-Bigas N, Plana M, Alonso MJ, Esteban M, Gómez CE. Marcos-Villar L, et al. Among authors: casasnovas jm. Emerg Microbes Infect. 2024 Dec;13(1):2387906. doi: 10.1080/22221751.2024.2387906. Epub 2024 Aug 8. Emerg Microbes Infect. 2024. PMID: 39087555 Free PMC article.
MVA-based vaccine candidates expressing SARS-CoV-2 prefusion-stabilized spike proteins of the Wuhan, Beta or Omicron BA.1 variants protect transgenic K18-hACE2 mice against Omicron infection and elicit robust and broad specific humoral and cellular immune responses.
Pérez P, Astorgano D, Albericio G, Flores S, Sánchez-Corzo C, Noriega MA, Sánchez-Cordón PJ, Labiod N, Delgado R, Casasnovas JM, Esteban M, García-Arriaza J. Pérez P, et al. Among authors: casasnovas jm. Front Immunol. 2024 Aug 29;15:1420304. doi: 10.3389/fimmu.2024.1420304. eCollection 2024. Front Immunol. 2024. PMID: 39267752 Free PMC article.
Molecular Basis for the Differential Function of HAVCR1 Mucin Variants.
Abbasi A, Costafreda MI, Ballesteros A, Jacques J, Tami C, Manangeeswaran M, Casasnovas JM, Kaplan G. Abbasi A, et al. Among authors: casasnovas jm. Biomedicines. 2024 Nov 19;12(11):2643. doi: 10.3390/biomedicines12112643. Biomedicines. 2024. PMID: 39595207 Free PMC article.
Intranasal administration of a single dose of MVA-based vaccine candidates against COVID-19 induced local and systemic immune responses and protects mice from a lethal SARS-CoV-2 infection.
Pérez P, Astorgano D, Albericio G, Flores S, Sánchez-Cordón PJ, Luczkowiak J, Delgado R, Casasnovas JM, Esteban M, García-Arriaza J. Pérez P, et al. Among authors: casasnovas jm. Front Immunol. 2022 Sep 12;13:995235. doi: 10.3389/fimmu.2022.995235. eCollection 2022. Front Immunol. 2022. PMID: 36172368 Free PMC article.
Nanobodies Protecting From Lethal SARS-CoV-2 Infection Target Receptor Binding Epitopes Preserved in Virus Variants Other Than Omicron.
Casasnovas JM, Margolles Y, Noriega MA, Guzmán M, Arranz R, Melero R, Casanova M, Corbera JA, Jiménez-de-Oya N, Gastaminza P, Garaigorta U, Saiz JC, Martín-Acebes MÁ, Fernández LÁ. Casasnovas JM, et al. Front Immunol. 2022 Apr 25;13:863831. doi: 10.3389/fimmu.2022.863831. eCollection 2022. Front Immunol. 2022. PMID: 35547740 Free PMC article.
78 results