Moore MP - Search Results

1

Hepatocyte-targeted siTAZ therapy lowers liver fibrosis in NASH diet-fed chimeric mice with hepatocyte-humanized livers.

Wang X, Moore MP, Shi H, Miyata Y, Donnelly SK, Radiloff DR, Tabas I. Wang X, et al. Among authors: moore mp. Mol Ther Methods Clin Dev. 2023 Nov 23;31:101165. doi: 10.1016/j.omtm.2023.101165. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 38144682 Free PMC article.

2

Circulating indian hedgehog is a marker of the hepatocyte-TAZ pathway in experimental NASH and is elevated in humans with NASH.

Moore MP, Wang X, Shi H, Meroni M, Cherubini A, Ronzoni L, Parks EJ, Ibdah JA, Rector RS, Valenti L, Dongiovanni P, Tabas I. Moore MP, et al. JHEP Rep. 2023 Feb 26;5(5):100716. doi: 10.1016/j.jhepr.2023.100716. eCollection 2023 May. JHEP Rep. 2023. PMID: 37035456 Free PMC article.

3

Low MBOAT7 expression, a genetic risk for MASH, promotes a profibrotic pathway involving hepatocyte TAZ upregulation.

Moore MP, Wang X, Kennelly JP, Shi H, Ishino Y, Kano K, Aoki J, Cherubini A, Ronzoni L, Guo X, Chalasani NP, Khalid S, Saleheen D, Mitsche MA, Rotter JI, Yates KP, Valenti L, Kono N, Tontonoz P, Tabas I. Moore MP, et al. Hepatology. 2024 May 22. doi: 10.1097/HEP.0000000000000933. Online ahead of print. Hepatology. 2024. PMID: 38776184

4

Critical Role for Hepatocyte-Specific eNOS in NAFLD and NASH.

Cunningham RP, Moore MP, Dashek RJ, Meers GM, Takahashi T, Sheldon RD, Wheeler AA, Diaz-Arias A, Ibdah JA, Parks EJ, Thyfault JP, Rector RS. Cunningham RP, et al. Among authors: moore mp. Diabetes. 2021 Nov;70(11):2476-2491. doi: 10.2337/db20-1228. Epub 2021 Aug 11. Diabetes. 2021. PMID: 34380696 Free PMC article.

5

A dietary ketone ester mitigates histological outcomes of NAFLD and markers of fibrosis in high-fat diet fed mice.

Moore MP, Cunningham RP, Davis RAH, Deemer SE, Roberts BM, Plaisance EP, Rector RS. Moore MP, et al. Am J Physiol Gastrointest Liver Physiol. 2021 Apr 1;320(4):G564-G572. doi: 10.1152/ajpgi.00259.2020. Epub 2021 Jan 27. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33501889 Free PMC article.

6

Curcumin supplementation mitigates NASH development and progression in female Wistar rats.

Cunningham RP, Moore MP, Moore AN, Healy JC, Roberts MD, Rector RS, Martin JS. Cunningham RP, et al. Among authors: moore mp, moore an. Physiol Rep. 2018 Jul;6(14):e13789. doi: 10.14814/phy2.13789. Physiol Rep. 2018. PMID: 30009570 Free PMC article.

7

Compromised hepatic mitochondrial fatty acid oxidation and reduced markers of mitochondrial turnover in human NAFLD.

Moore MP, Cunningham RP, Meers GM, Johnson SA, Wheeler AA, Ganga RR, Spencer NM, Pitt JB, Diaz-Arias A, Swi AIA, Hammoud GM, Ibdah JA, Parks EJ, Rector RS. Moore MP, et al. Hepatology. 2022 Nov;76(5):1452-1465. doi: 10.1002/hep.32324. Epub 2022 Apr 14. Hepatology. 2022. PMID: 35000203 Free PMC article.

8

The impact of time-restricted feeding in combination with aerobic exercise on weight gain and markers of hepatic metabolism.

Moore MP, Wieschhaus NE, Alessi IG. Moore MP, et al. J Physiol. 2022 May;600(10):2277-2278. doi: 10.1113/JP283020. Epub 2022 Apr 13. J Physiol. 2022. PMID: 35362100 Free article. No abstract available.

9

Isotope Labeling and Biochemical Assessment of Liver-Triacylglycerol in Patients with Different Levels of Histologically-Graded Liver Disease.

Syed-Abdul MM, Moore MP, Wheeler AA, Ganga RR, Diaz-Arias A, Petroski GF, Rector RS, Ibdah JA, Parks EJ. Syed-Abdul MM, et al. Among authors: moore mp. J Nutr. 2023 Dec;153(12):3418-3429. doi: 10.1016/j.tjnut.2023.09.018. Epub 2023 Sep 27. J Nutr. 2023. PMID: 37774841 Free PMC article.

10

Histological improvements following energy restriction and exercise: The role of insulin resistance in resolution of MASH.

Mucinski JM, Salvador AF, Moore MP, Fordham TM, Anderson JM, Shryack G, Cunningham RP, Lastra G, Gaballah AH, Diaz-Arias A, Ibdah JA, Rector RS, Parks EJ. Mucinski JM, et al. Among authors: moore mp. J Hepatol. 2024 Nov;81(5):781-793. doi: 10.1016/j.jhep.2024.06.017. Epub 2024 Jun 22. J Hepatol. 2024. PMID: 38914313 Clinical Trial.

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