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210 results

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Page 1
Tumor necrosis factor α promotes clonal dominance of KIT D816V+ cells in mastocytosis: role of survivin and impact on prognosis.
Greiner G, Witzeneder N, Klein K, Tangermann S, Kodajova P, Jaeger E, Ratzinger F, Gerner MC, Jawhar M, Baumgartner S, Fruehwirth K, Schmetterer KG, Zuber J, Gleixner KV, Mayerhofer M, Schwarzinger I, Simonitsch-Klupp I, Esterbauer H, Baer C, Walter W, Meggendorfer M, Strassl R, Haferlach T, Hartmann K, Kenner L, Sperr WR, Reiter A, Sexl V, Arock M, Valent P, Hoermann G. Greiner G, et al. Among authors: sexl v. Blood. 2024 Mar 14;143(11):1006-1017. doi: 10.1182/blood.2023020515. Blood. 2024. PMID: 38142424
Resting natural killer cell homeostasis relies on tryptophan/NAD+ metabolism and HIF-1α.
Pelletier A, Nelius E, Fan Z, Khatchatourova E, Alvarado-Diaz A, He J, Krzywinska E, Sobecki M, Nagarajan S, Kerdiles Y, Fandrey J, Gotthardt D, Sexl V, de Bock K, Stockmann C. Pelletier A, et al. Among authors: sexl v. EMBO Rep. 2023 Jun 5;24(6):e56156. doi: 10.15252/embr.202256156. Epub 2023 Mar 29. EMBO Rep. 2023. PMID: 36987917 Free PMC article.
Fibrolytic vaccination against ADAM12 reduces desmoplasia in preclinical pancreatic adenocarcinomas.
Chen J, Sobecki M, Krzywinska E, Thierry K, Masmoudi M, Nagarajan S, Fan Z, He J, Ferapontova I, Nelius E, Seehusen F, Gotthardt D, Takeda N, Sommer L, Sexl V, Münz C, DeNardo D, Hennino A, Stockmann C. Chen J, et al. Among authors: sexl v. EMBO Mol Med. 2024 Dec;16(12):3033-3056. doi: 10.1038/s44321-024-00157-4. Epub 2024 Oct 30. EMBO Mol Med. 2024. PMID: 39478152 Free PMC article.
A Lack of Diversity, Equity, and Inclusion in Clinical Research Has Direct Impact on Patient Care.
El-Galaly TC, Gaidzik VI, Gaman MA, Antic D, Okosun J, Copland M, Sexl V, Fielding AK, Doeswijk R, Parker H, Dreyling M, Döhner K, Almeida AM, Macintyre E, Gribben JG, Grønbæk K. El-Galaly TC, et al. Among authors: sexl v. Hemasphere. 2023 Feb 21;7(3):e842. doi: 10.1097/HS9.0000000000000842. eCollection 2023 Mar. Hemasphere. 2023. PMID: 36844176 Free PMC article. No abstract available.
Cyclin C promotes development and progression of B-cell acute lymphoblastic leukemia by counteracting p53-mediated stress responses.
Trifinopoulos J, List J, Klampfl T, Klein K, Prchal-Murphy M, Witalisz-Siepracka A, Bellutti F, Fava LL, Heller G, Stummer S, Testori P, Den Boer ML, Boer JM, Marinovic S, Hoermann G, Walter W, Villunger A, Sicinski P, Sexl V, Gotthardt D. Trifinopoulos J, et al. Among authors: sexl v. Haematologica. 2024 Oct 10. doi: 10.3324/haematol.2024.285701. Online ahead of print. Haematologica. 2024. PMID: 39385738 Free article.
Impact of protein and small molecule interactions on kinase conformations.
Kugler V, Schwaighofer S, Feichtner A, Enzler F, Fleischmann J, Strich S, Schwarz S, Wilson R, Tschaikner P, Troppmair J, Sexl V, Meier P, Kaserer T, Stefan E. Kugler V, et al. Among authors: sexl v. Elife. 2024 Aug 1;13:RP94755. doi: 10.7554/eLife.94755. Elife. 2024. PMID: 39088265 Free PMC article.
Kinase-inactivated CDK6 preserves the long-term functionality of adult hematopoietic stem cells.
Mayer IM, Doma E, Klampfl T, Prchal-Murphy M, Kollmann S, Schirripa A, Scheiblecker L, Zojer M, Kunowska N, Gebrail L, Shaw LE, Mann U, Farr A, Grausenburger R, Heller G, Zebedin-Brandl E, Farlik M, Malumbres M, Sexl V, Kollmann K. Mayer IM, et al. Among authors: sexl v. Blood. 2024 Jul 11;144(2):156-170. doi: 10.1182/blood.2023021985. Blood. 2024. PMID: 38684032 Free PMC article.
JAK-STAT signaling maintains homeostasis in T cells and macrophages.
Fortelny N, Farlik M, Fife V, Gorki AD, Lassnig C, Maurer B, Meissl K, Dolezal M, Boccuni L, Ravi Sundar Jose Geetha A, Akagha MJ, Karjalainen A, Shoebridge S, Farhat A, Mann U, Jain R, Tikoo S, Zila N, Esser-Skala W, Krausgruber T, Sitnik K, Penz T, Hladik A, Suske T, Zahalka S, Senekowitsch M, Barreca D, Halbritter F, Macho-Maschler S, Weninger W, Neubauer HA, Moriggl R, Knapp S, Sexl V, Strobl B, Decker T, Müller M, Bock C. Fortelny N, et al. Among authors: sexl v. Nat Immunol. 2024 May;25(5):847-859. doi: 10.1038/s41590-024-01804-1. Epub 2024 Apr 24. Nat Immunol. 2024. PMID: 38658806 Free PMC article.
210 results