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327 results

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Page 1
The Cerebroventricular Environment Modifies CAR T Cells for Potent Activity against Both Central Nervous System and Systemic Lymphoma.
Wang X, Huynh C, Urak R, Weng L, Walter M, Lim L, Vyas V, Chang WC, Aguilar B, Brito A, Sarkissian A, Bandara NA, Yang L, Wang J, Wu X, Zhang J, Priceman SJ, Qin H, Kwak LW, Budde LE, Thomas SH, Clark MC, Popplewell L, Siddiqi T, Brown CE, Forman SJ. Wang X, et al. Among authors: vyas v. Cancer Immunol Res. 2021 Jan;9(1):75-88. doi: 10.1158/2326-6066.CIR-20-0236. Epub 2020 Oct 22. Cancer Immunol Res. 2021. PMID: 33093217 Free PMC article.
CD19-directed CAR T-cell therapy for treatment of primary CNS lymphoma.
Siddiqi T, Wang X, Blanchard MS, Wagner JR, Popplewell LL, Budde LE, Stiller TL, Clark MC, Lim L, Vyas V, Brown CE, Forman SJ. Siddiqi T, et al. Among authors: vyas v. Blood Adv. 2021 Oct 26;5(20):4059-4063. doi: 10.1182/bloodadvances.2020004106. Blood Adv. 2021. PMID: 34492703 Free PMC article.
Large-scale manufacturing and characterization of CMV-CD19CAR T cells.
Wang X, Urak R, Walter M, Guan M, Han T, Vyas V, Chien SH, Gittins B, Clark MC, Mokhtari S, Cardoso A, Diamond DJ, Zaia J, Forman SJ, Nakamura R. Wang X, et al. Among authors: vyas v. J Immunother Cancer. 2022 Jan;10(1):e003461. doi: 10.1136/jitc-2021-003461. J Immunother Cancer. 2022. PMID: 35027426 Free PMC article.
CD19/BAFF-R dual-targeted CAR T cells for the treatment of mixed antigen-negative variants of acute lymphoblastic leukemia.
Wang X, Dong Z, Awuah D, Chang WC, Cheng WA, Vyas V, Cha SC, Anderson AJ, Zhang T, Wang Z, Szymura SJ, Kuang BZ, Clark MC, Aldoss I, Forman SJ, Kwak LW, Qin H. Wang X, et al. Among authors: vyas v. Leukemia. 2022 Apr;36(4):1015-1024. doi: 10.1038/s41375-021-01477-x. Epub 2022 Jan 18. Leukemia. 2022. PMID: 35039637 Free PMC article.
3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells.
Wang Z, McWilliams-Koeppen HP, Reza H, Ostberg JR, Chen W, Wang X, Huynh C, Vyas V, Chang WC, Starr R, Wagner JR, Aguilar B, Yang X, Wu X, Wang J, Chen W, Koelker-Wolfe E, Seet CS, Montel-Hagen A, Crooks GM, Forman SJ, Brown CE. Wang Z, et al. Among authors: vyas v. Cell Stem Cell. 2022 Apr 7;29(4):515-527.e8. doi: 10.1016/j.stem.2022.02.009. Epub 2022 Mar 11. Cell Stem Cell. 2022. PMID: 35278370 Free PMC article.
Pre-clinical data supporting immunotherapy for HIV using CMV-HIV-specific CAR T cells with CMV vaccine.
Guan M, Lim L, Holguin L, Han T, Vyas V, Urak R, Miller A, Browning DL, Echavarria L, Li S, Li S, Chang WC, Scott T, Yazaki P, Morris KV, Cardoso AA, Blanchard MS, Le Verche V, Forman SJ, Zaia JA, Burnett JC, Wang X. Guan M, et al. Among authors: vyas v. Mol Ther Methods Clin Dev. 2022 Apr 13;25:344-359. doi: 10.1016/j.omtm.2022.04.007. eCollection 2022 Jun 9. Mol Ther Methods Clin Dev. 2022. PMID: 35573050 Free PMC article.
Favorable Activity and Safety Profile of Memory-Enriched CD19-Targeted Chimeric Antigen Receptor T-Cell Therapy in Adults with High-Risk Relapsed/Refractory ALL.
Aldoss I, Khaled SK, Wang X, Palmer J, Wang Y, Wagner JR, Clark MC, Simpson J, Paul J, Vyas V, Chien SH, Stein A, Pullarkat V, Salhotra A, Al Malki MM, Aribi A, Sandhu K, Thomas SH, Budde LE, Marcucci G, Brown CE, Forman SJ. Aldoss I, et al. Among authors: vyas v. Clin Cancer Res. 2023 Feb 16;29(4):742-753. doi: 10.1158/1078-0432.CCR-22-2038. Clin Cancer Res. 2023. PMID: 36255386 Free PMC article.
327 results