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Page 1
Establishment and Thorough Characterization of Xenograft (PDX) Models Derived from Patients with Pancreatic Cancer for Molecular Analyses and Chemosensitivity Testing.
Behrens D, Pfohl U, Conrad T, Becker M, Brzezicha B, Büttner B, Wagner S, Hallas C, Lawlor R, Khazak V, Linnebacher M, Wartmann T, Fichtner I, Hoffmann J, Dahlmann M, Walther W. Behrens D, et al. Among authors: brzezicha b. Cancers (Basel). 2023 Dec 8;15(24):5753. doi: 10.3390/cancers15245753. Cancers (Basel). 2023. PMID: 38136299 Free PMC article.
Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer.
Demel UM, Böger M, Yousefian S, Grunert C, Zhang L, Hotz PW, Gottschlich A, Köse H, Isaakidis K, Vonficht D, Grünschläger F, Rohleder E, Wagner K, Dönig J, Igl V, Brzezicha B, Baumgartner F, Habringer S, Löber J, Chapuy B, Weidinger C, Kobold S, Haas S, Busse AB, Müller S, Wirth M, Schick M, Keller U. Demel UM, et al. Among authors: brzezicha b. J Clin Invest. 2022 May 2;132(9):e152383. doi: 10.1172/JCI152383. J Clin Invest. 2022. PMID: 35499080 Free PMC article.
Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models.
Dahlmann M, Gambara G, Brzezicha B, Popp O, Pachmayr E, Wedeken L, Pflaume A, Mokritzkij M, Gül-Klein S, Brandl A, Schweiger-Eisbacher C, Mertins P, Hoffmann J, Keilholz U, Walther W, Regenbrecht C, Rau B, Stein U. Dahlmann M, et al. Among authors: brzezicha b. Mol Cancer. 2021 Oct 21;20(1):129. doi: 10.1186/s12943-021-01430-7. Mol Cancer. 2021. PMID: 34670579 Free PMC article. No abstract available.
Pattern Recognition Receptors: Significance of Expression in the Liver.
Żeromski J, Kierepa A, Brzezicha B, Kowala-Piaskowska A, Mozer-Lisewska I. Żeromski J, et al. Among authors: brzezicha b. Arch Immunol Ther Exp (Warsz). 2020 Sep 17;68(5):29. doi: 10.1007/s00005-020-00595-1. Arch Immunol Ther Exp (Warsz). 2020. PMID: 32944845 Free PMC article. Review.
Animal models for personalized treatment options.
Fichtner I, Klinghammer K, Behrens D, Flechsig S, Rolff J, Becker M, Wulf-Goldenberg A, Stecklum M, Rivera M, Brzezicha B, Jandrig B, Hoffmann J. Fichtner I, et al. Among authors: brzezicha b. Int J Clin Pharmacol Ther. 2017 Aug;55(8):698-700. doi: 10.5414/CPXCES15EA09. Int J Clin Pharmacol Ther. 2017. PMID: 28696202 No abstract available.
A comprehensively characterized large panel of head and neck cancer patient-derived xenografts identifies the mTOR inhibitor everolimus as potential new treatment option.
Klinghammer K, Raguse JD, Plath T, Albers AE, Joehrens K, Zakarneh A, Brzezicha B, Wulf-Goldenberg A, Keilholz U, Hoffmann J, Fichtner I. Klinghammer K, et al. Among authors: brzezicha b. Int J Cancer. 2015 Jun 15;136(12):2940-8. doi: 10.1002/ijc.29344. Epub 2014 Nov 26. Int J Cancer. 2015. PMID: 25404014
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