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230 results

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Natural Products with Tandem Anti-inflammatory, Immunomodulatory and Anti-SARS-CoV/2 Effects: A Drug Discovery Perspective against SARS-CoV-2.
da Cunha LNOL, Tizziani T, Souza GB, Moreira MA, Neto JSS, Dos Santos CVD, de Carvalho MG, Dalmarco EM, Turqueti LB, Scotti MT, Scotti L, de Assis FF, Braga AL, Sandjo LP. da Cunha LNOL, et al. Among authors: braga al. Curr Med Chem. 2022;29(14):2530-2564. doi: 10.2174/0929867328666210726094955. Curr Med Chem. 2022. PMID: 34313197
Studies of Cytotoxicity Effects, SARS-CoV-2 Main Protease Inhibition, and in Silico Interactions of Synthetic Chalcones.
Guterres Fernandes OL, Tizziani T, Dambrós BP, Ferreira de Sousa N, Mansur Pontes CL, da Silva LAL, Escorteganha Pollo LA, de Assis FF, Scotti MT, Scotti L, Braga AL, Steindel M, Sandjo LP. Guterres Fernandes OL, et al. Among authors: braga al. Chem Biodivers. 2023 Mar;20(3):e202201151. doi: 10.1002/cbdv.202201151. Epub 2023 Feb 14. Chem Biodivers. 2023. PMID: 36740573
Inhibitory effects of 190 compounds against SARS-CoV-2 Mpr o protein: Molecular docking interactions.
Souza GB, Sens L, Hammerschmidt SJ, de Sousa NF, de Carvalho MAG, Dos Santos CVD, Tizziani T, Moreira MA, Pollo LAE, Martin EF, Neto JSS, Biavatti MW, de Assis FF, Ngadjui BT, Simo IK, Ambassa P, Scotti MT, Scotti L, Braga AL, Schirmeister T, Sandjo LP. Souza GB, et al. Among authors: braga al. Arch Pharm (Weinheim). 2023 Aug;356(8):e2300207. doi: 10.1002/ardp.202300207. Epub 2023 May 31. Arch Pharm (Weinheim). 2023. PMID: 37255416
Inhibitory Effects of Mangifera indica Secondary Metabolites and Their Synthetic Derivatives against SARS-CoV-2 Mpro and NS2B/NS3 (ZIKV and DENV-2).
B Souza G, M Pontes CL, de O Costa G, F de Sousa N, Tizziani T, E Pollo LA, Dambrós BP, Scotti MT, Steindel M, Braga AL, Schirmeister T, F de Assis F, Sandjo LP. B Souza G, et al. Among authors: braga al. ACS Omega. 2024 Oct 24;9(44):44624-44638. doi: 10.1021/acsomega.4c07148. eCollection 2024 Nov 5. ACS Omega. 2024. PMID: 39524678 Free PMC article.
It takes two to tango: synthesis of cytotoxic quinones containing two redox active centers with potential antitumor activity.
Lima DJB, Almeida RG, Jardim GAM, Barbosa BPA, Santos ACC, Valença WO, Scheide MR, Gatto CC, de Carvalho GGC, Costa PMS, Pessoa C, Pereira CLM, Jacob C, Braga AL, da Silva Júnior EN. Lima DJB, et al. Among authors: braga al. RSC Med Chem. 2021 Aug 12;12(10):1709-1721. doi: 10.1039/d1md00168j. eCollection 2021 Oct 20. RSC Med Chem. 2021. PMID: 34778772 Free PMC article.
Chalcone Derivatives as Antibacterial Agents: An Updated Overview.
de Oliveira AS, Cenci AR, Gonçalves L, Thedy MEC, Justino A, Braga AL, Meier L. de Oliveira AS, et al. Among authors: braga al. Curr Med Chem. 2024;31(17):2314-2329. doi: 10.2174/0929867330666230220140819. Curr Med Chem. 2024. PMID: 36803761 Review.
230 results