Thielen A - Search Results

1

Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed models.

Hake A, Germann A, de Beer C, Thielen A, Däumer M, Preiser W, von Briesen H, Pfeifer N. Hake A, et al. Among authors: thielen a. PLoS Comput Biol. 2023 Dec 21;19(12):e1010355. doi: 10.1371/journal.pcbi.1010355. eCollection 2023 Dec. PLoS Comput Biol. 2023. PMID: 38127856 Free PMC article.

2

In-depth analysis of G-to-A hypermutation rate in HIV-1 env DNA induced by endogenous APOBEC3 proteins using massively parallel sequencing.

Knoepfel SA, Di Giallonardo F, Däumer M, Thielen A, Metzner KJ. Knoepfel SA, et al. Among authors: thielen a. J Virol Methods. 2011 Feb;171(2):329-38. doi: 10.1016/j.jviromet.2010.11.016. Epub 2010 Nov 24. J Virol Methods. 2011. PMID: 21111003

3

Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis.

Däumer M, Kaiser R, Klein R, Lengauer T, Thiele B, Thielen A. Däumer M, et al. Among authors: thielen a. BMC Med Inform Decis Mak. 2011 May 13;11:30. doi: 10.1186/1472-6947-11-30. BMC Med Inform Decis Mak. 2011. PMID: 21569501 Free PMC article.

4

Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach.

Sierra S, Kaiser R, Lübke N, Thielen A, Schuelter E, Heger E, Däumer M, Reuter S, Esser S, Fätkenheuer G, Pfister H, Oette M, Lengauer T. Sierra S, et al. Among authors: thielen a. J Vis Exp. 2011 Dec 1;(58):3264. doi: 10.3791/3264. J Vis Exp. 2011. PMID: 22157596 Free PMC article.

5

Therapeutic Immune Recovery and Reduction of CXCR4-Tropic HIV-1.

Bader J, Däumer M, Schöni-Affolter F, Böni J, Gorgievski-Hrisoho M, Martinetti G, Thielen A, Klimkait T; Swiss HIV Cohort Study. Bader J, et al. Among authors: thielen a. Clin Infect Dis. 2017 Feb 1;64(3):295-300. doi: 10.1093/cid/ciw737. Epub 2016 Nov 12. Clin Infect Dis. 2017. PMID: 27838645 Free article.

6

Impact of the HIV-1 genetic background and HIV-1 population size on the evolution of raltegravir resistance.

Fun A, Leitner T, Vandekerckhove L, Däumer M, Thielen A, Buchholz B, Hoepelman AIM, Gisolf EH, Schipper PJ, Wensing AMJ, Nijhuis M. Fun A, et al. Among authors: thielen a. Retrovirology. 2018 Jan 5;15(1):1. doi: 10.1186/s12977-017-0384-z. Retrovirology. 2018. PMID: 29304821 Free PMC article.

7

geno2pheno[ngs-freq]: a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data.

Döring M, Büch J, Friedrich G, Pironti A, Kalaghatgi P, Knops E, Heger E, Obermeier M, Däumer M, Thielen A, Kaiser R, Lengauer T, Pfeifer N. Döring M, et al. Among authors: thielen a. Nucleic Acids Res. 2018 Jul 2;46(W1):W271-W277. doi: 10.1093/nar/gky349. Nucleic Acids Res. 2018. PMID: 29718426 Free PMC article.

8

Rapid Rebound of a Preexisting CXCR4-tropic Human Immunodeficiency Virus Variant After Allogeneic Transplantation With CCR5 Δ32 Homozygous Stem Cells.

Verheyen J, Thielen A, Lübke N, Dirks M, Widera M, Dittmer U, Kordelas L, Däumer M, de Jong DCM, Wensing AMJ, Kaiser R, Nijhuis M, Esser S. Verheyen J, et al. Among authors: thielen a. Clin Infect Dis. 2019 Feb 1;68(4):684-687. doi: 10.1093/cid/ciy565. Clin Infect Dis. 2019. PMID: 30020413

9

Failure of Dolutegravir First-Line ART with Selection of Virus Carrying R263K and G118R.

Lübke N, Jensen B, Hüttig F, Feldt T, Walker A, Thielen A, Däumer M, Obermeier M, Kaiser R, Knops E, Heger E, Sierra S, Oette M, Lengauer T, Timm J, Häussinger D. Lübke N, et al. Among authors: thielen a. N Engl J Med. 2019 Aug 29;381(9):887-889. doi: 10.1056/NEJMc1806554. N Engl J Med. 2019. PMID: 31461601 No abstract available.

10

Adapting the geno2pheno[coreceptor] tool to HIV-1 subtype CRF01_AE by phenotypic validation using clinical isolates from South-East Asia.

Marty N, Saeng-Aroon S, Heger E, Thielen A, Obermeier M, Pfeifer N, Kaiser R, Klimkait T. Marty N, et al. Among authors: thielen a. J Clin Virol. 2021 Mar;136:104755. doi: 10.1016/j.jcv.2021.104755. Epub 2021 Feb 9. J Clin Virol. 2021. PMID: 33639408 Free article.

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