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Modification of picornavirus genomic RNA using 'click' chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA.
Langereis MA, Feng Q, Nelissen FH, Virgen-Slane R, van der Heden van Noort GJ, Maciejewski S, Filippov DV, Semler BL, van Delft FL, van Kuppeveld FJ. Langereis MA, et al. Among authors: van der heden van noort gj, van delft fl, van kuppeveld fj. Nucleic Acids Res. 2014 Feb;42(4):2473-82. doi: 10.1093/nar/gkt1162. Epub 2013 Nov 15. Nucleic Acids Res. 2014. PMID: 24243841 Free PMC article.
Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler.
Liwocha J, Krist DT, van der Heden van Noort GJ, Hansen FM, Truong VH, Karayel O, Purser N, Houston D, Burton N, Bostock MJ, Sattler M, Mann M, Harrison JS, Kleiger G, Ovaa H, Schulman BA. Liwocha J, et al. Among authors: van der heden van noort gj. Nat Chem Biol. 2021 Mar;17(3):272-279. doi: 10.1038/s41589-020-00696-0. Epub 2020 Dec 7. Nat Chem Biol. 2021. PMID: 33288957 Free PMC article.
K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap.
van Tilburg GBA, Murachelli AG, Fish A, van der Heden van Noort GJ, Ovaa H, Sixma TK. van Tilburg GBA, et al. Among authors: van der heden van noort gj. Cell Chem Biol. 2021 Feb 18;28(2):191-201.e8. doi: 10.1016/j.chembiol.2020.11.005. Epub 2020 Nov 24. Cell Chem Biol. 2021. PMID: 33238157 Free article.
State of the art in (semi-)synthesis of Ubiquitin- and Ubiquitin-like tools.
Huppelschoten Y, van der Heden van Noort GJ. Huppelschoten Y, et al. Among authors: van der heden van noort gj. Semin Cell Dev Biol. 2022 Dec;132:74-85. doi: 10.1016/j.semcdb.2021.11.025. Epub 2021 Dec 24. Semin Cell Dev Biol. 2022. PMID: 34961664 Free article. Review.
Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5.
Hehl LA, Horn-Ghetko D, Prabu JR, Vollrath R, Vu DT, Pérez Berrocal DA, Mulder MPC, van der Heden van Noort GJ, Schulman BA. Hehl LA, et al. Among authors: van der heden van noort gj. Nat Chem Biol. 2024 Feb;20(2):190-200. doi: 10.1038/s41589-023-01414-2. Epub 2023 Aug 24. Nat Chem Biol. 2024. PMID: 37620400 Free PMC article.
54 results