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Inhibition of the melanocortin-3 receptor (MC3R) causes generalized sensitization to anorectic agents.
Dahir NS, Gui Y, Wu Y, Sweeney PR, Williams SY, Gimenez LE, Sawyer TK, Joy ST, Mapp AK, Cone RD. Dahir NS, et al. Among authors: joy st. bioRxiv [Preprint]. 2023 Dec 7:2023.12.05.570114. doi: 10.1101/2023.12.05.570114. bioRxiv. 2023. Update in: J Clin Invest. 2024 Jul 15;134(14):e178250. doi: 10.1172/JCI178250 PMID: 38106197 Free PMC article. Updated. Preprint.
The melanocortin-3 receptor is a pharmacological target for the regulation of anorexia.
Sweeney P, Bedenbaugh MN, Maldonado J, Pan P, Fowler K, Williams SY, Gimenez LE, Ghamari-Langroudi M, Downing G, Gui Y, Hadley CK, Joy ST, Mapp AK, Simerly RB, Cone RD. Sweeney P, et al. Among authors: joy st. Sci Transl Med. 2021 Apr 21;13(590):eabd6434. doi: 10.1126/scitranslmed.abd6434. Sci Transl Med. 2021. PMID: 33883274 Free PMC article.
Copper-Mediated Radiocyanation of Unprotected Amino Acids and Peptides.
Sharninghausen LS, Preshlock S, Joy ST, Horikawa M, Shao X, Winton WP, Stauff J, Kaur T, Koeppe RA, Mapp AK, Scott PJH, Sanford MS. Sharninghausen LS, et al. Among authors: joy st. J Am Chem Soc. 2022 Apr 27;144(16):7422-7429. doi: 10.1021/jacs.2c01959. Epub 2022 Apr 18. J Am Chem Soc. 2022. PMID: 35437016 Free PMC article.
Inhibition of CREB Binding and Function with a Dual-Targeting Ligand.
Liu Y, Joy ST, Henley MJ, Croskey A, Yates JA, Merajver SD, Mapp AK. Liu Y, et al. Among authors: joy st. Biochemistry. 2024 Jan 2;63(1):1-8. doi: 10.1021/acs.biochem.3c00469. Epub 2023 Dec 12. Biochemistry. 2024. PMID: 38086054 Free PMC article.
16 results