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Page 1
Mitochondrial DNA Copy Number Variation in Asthma Risk, Severity, and Exacerbations.
Xu W, Hong YS, Hu B, Comhair SAA, Janocha AJ, Zein JG, Chen R, Meyers DA, Mauger DT, Ortega VE, Bleecker ER, Castro M, Denlinger LC, Fahy JV, Israel E, Levy BD, Jarjour NN, Moore WC, Wenzel SE, Gaston B, Liu C, Arking DE, Erzurum SC; National Heart, Lung, and Blood Institute (NHLBI) Severe Asthma Research Program (SARP) and TOPMed mtDNA Working Group in NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Xu W, et al. Among authors: mauger dt. medRxiv [Preprint]. 2023 Dec 5:2023.12.05.23299392. doi: 10.1101/2023.12.05.23299392. medRxiv. 2023. Update in: J Allergy Clin Immunol. 2024 Sep 3:S0091-6749(24)00906-0. doi: 10.1016/j.jaci.2024.08.022 PMID: 38106101 Free PMC article. Updated. Preprint.
Bronchial epithelial cell transcriptional responses to inhaled corticosteroids dictate severe asthmatic outcomes.
Ginebaugh SP, Hagner M, Ray A, Erzurum SC, Comhair SAA, Denlinger LC, Jarjour NN, Castro M, Woodruff PG, Christenson SA, Bleecker ER, Meyers DA, Hastie AT, Moore WC, Mauger DT, Israel E, Levy BD, Wenzel SE, Camiolo MJ. Ginebaugh SP, et al. Among authors: mauger dt. J Allergy Clin Immunol. 2023 Jun;151(6):1513-1524. doi: 10.1016/j.jaci.2023.01.028. Epub 2023 Feb 14. J Allergy Clin Immunol. 2023. PMID: 36796454 Free PMC article.
CCL5 is a potential bridge between type 1 and type 2 inflammation in asthma.
Gauthier M, Kale SL, Oriss TB, Gorry M, Ramonell RP, Dalton K, Ray P, Fahy JV, Seibold MA, Castro M, Jarjour N, Gaston B, Bleecker ER, Meyers DA, Moore W, Hastie AT, Israel E, Levy BD, Mauger D, Erzurum S, Comhair SA, Wenzel SE, Ray A. Gauthier M, et al. J Allergy Clin Immunol. 2023 Jul;152(1):94-106.e12. doi: 10.1016/j.jaci.2023.02.028. Epub 2023 Mar 8. J Allergy Clin Immunol. 2023. PMID: 36893862 Free PMC article.
Investigations of a combination of atopic status and age of asthma onset identify asthma subphenotypes.
Li H, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Wenzel SE, Zein J, Bleecker ER, Meyers DA, Chen Y, Li X; NHLBI Severe Asthma Research Program (SARP). Li H, et al. Among authors: mauger dt. J Asthma. 2023 Oct;60(10):1843-1852. doi: 10.1080/02770903.2023.2193634. Epub 2023 Apr 21. J Asthma. 2023. PMID: 36940238 Free PMC article.
Genetic analyses of chr11p15.5 region identify MUC5AC-MUC5B associated with asthma-related phenotypes.
Li X, Li H, Christenson SA, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Zein J, Kaminski N, Wenzel SE, Woodruff PG, Bleecker ER, Meyers DA; NHLBI Severe Asthma Research Program (SARP). Li X, et al. Among authors: mauger dt. J Asthma. 2023 Oct;60(10):1824-1835. doi: 10.1080/02770903.2023.2193631. Epub 2023 Apr 21. J Asthma. 2023. PMID: 36946148 Free PMC article.
A Novel Air Trapping Segment Score Identifies Opposing Effects of Obesity and Eosinophilia on Air Trapping in Asthma.
Leung C, Tang M, Huang BK, Fain SB, Hoffman EA, Choi J, Dunican EM, Mauger DT, Denlinger LC, Jarjour NN, Israel E, Levy BD, Wenzel SE, Sumino K, Hastie AT, Schirm J, McCulloch CE, Peters MC, Woodruff PG, Sorkness RL, Castro M, Fahy JV. Leung C, et al. Among authors: mauger dt. Am J Respir Crit Care Med. 2024 May 15;209(10):1196-1207. doi: 10.1164/rccm.202305-0802OC. Am J Respir Crit Care Med. 2024. PMID: 38113166
Persistent mucus plugs in proximal airways are consequential for airflow limitation in asthma.
Huang BK, Elicker BM, Henry TS, Kallianos KG, Hahn LD, Tang M, Heng F, McCulloch CE, Bhakta NR, Majumdar S, Choi J, Denlinger LC, Fain SB, Hastie AT, Hoffman EA, Israel E, Jarjour NN, Levy BD, Mauger DT, Sumino K, Wenzel SE, Castro M, Woodruff PG, Fahy JV, Sarp FTNSARP. Huang BK, et al. Among authors: mauger dt. JCI Insight. 2024 Feb 8;9(3):e174124. doi: 10.1172/jci.insight.174124. JCI Insight. 2024. PMID: 38127464 Free PMC article.
Protein-Protein interactive networks identified in bronchoalveolar lavage of severe compared to nonsevere asthma.
Hastie AT, Bishop AC, Khan MS, Bleecker ER, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Israel E, Levy BD, Mauger DT, Meyers DA, Moore WC, Ortega VE, Peters SP, Wenzel SE, Steele CH. Hastie AT, et al. Among authors: mauger dt. Clin Exp Allergy. 2024 Apr;54(4):265-277. doi: 10.1111/cea.14447. Epub 2024 Jan 22. Clin Exp Allergy. 2024. PMID: 38253462
A novel DNase assay reveals low DNase activity in severe asthma.
Charbit AR, Liegeois MA, Raymond WW, Comhair SAA, Johansson MW, Hastie AT, Bleecker ER, Fajt M, Castro M, Sumino K, Erzurum SC, Israel E, Jarjour NN, Mauger DT, Moore WC, Wenzel SE, Woodruff PG, Levy BD, Tang MC, Fahy JV. Charbit AR, et al. Among authors: mauger dt. Am J Physiol Lung Cell Mol Physiol. 2024 Jun 1;326(6):L796-L804. doi: 10.1152/ajplung.00081.2024. Epub 2024 Apr 23. Am J Physiol Lung Cell Mol Physiol. 2024. PMID: 38651338
A common polymorphism in the Intelectin-1 gene influences mucus plugging in severe asthma.
Everman JL, Sajuthi SP, Liegeois MA, Jackson ND, Collet EH, Peters MC, Chioccioli M, Moore CM, Patel BB, Dyjack N, Powell R, Rios C, Montgomery MT, Eng C, Elhawary JR, Mak ACY, Hu D, Huntsman S, Salazar S, Feriani L, Fairbanks-Mahnke A, Zinnen GL, Michel CR, Gomez J, Zhang X, Medina V, Chu HW, Cicuta P, Gordon ED, Zeitlin P, Ortega VE, Reisdorph N, Dunican EM, Tang M, Elicker BM, Henry TS, Bleecker ER, Castro M, Erzurum SC, Israel E, Levy BD, Mauger DT, Meyers DA, Sumino K, Gierada DS, Hastie AT, Moore WC, Denlinger LC, Jarjour NN, Schiebler ML, Wenzel SE, Woodruff PG, Rodriguez-Santana J, Pearson CG, Burchard EG, Fahy JV, Seibold MA. Everman JL, et al. Among authors: mauger dt. Nat Commun. 2024 May 9;15(1):3900. doi: 10.1038/s41467-024-48034-5. Nat Commun. 2024. PMID: 38724552 Free PMC article.
165 results