Huang L - Search Results

1

Discovery of a Hidden Pocket beneath the NES Groove by Novel Noncovalent CRM1 Inhibitors.

Li C, Zhang Q, Huang W, Huang L, Long Q, Lei Y, Jia D, Yang S, Yang Y, Zhang X, Sun Q. Li C, et al. Among authors: huang l, huang w. J Med Chem. 2023 Dec 28;66(24):17044-17058. doi: 10.1021/acs.jmedchem.3c01867. Epub 2023 Dec 18. J Med Chem. 2023. PMID: 38105606

2

Structure-Based Discovery of N-Sulfonylpiperidine-3-Carboxamides as Novel Capsid Assembly Modulators for Potent Inhibition of HBV Replication.

Yang Y, Yan Y, Yin J, Hu J, Cai X, Hu J, Xia J, Wang K, Tang N, Huang L. Yang Y, et al. Among authors: huang l. Viruses. 2022 Feb 8;14(2):348. doi: 10.3390/v14020348. Viruses. 2022. PMID: 35215939 Free PMC article.

3

O-GlcNAcylation of YTHDF2 promotes HBV-related hepatocellular carcinoma progression in an N⁶-methyladenosine-dependent manner.

Yang Y, Yan Y, Yin J, Tang N, Wang K, Huang L, Hu J, Feng Z, Gao Q, Huang A. Yang Y, et al. Among authors: huang l, huang a. Signal Transduct Target Ther. 2023 Feb 10;8(1):63. doi: 10.1038/s41392-023-01316-8. Signal Transduct Target Ther. 2023. PMID: 36765030 Free PMC article.

4

Synthesis and evaluation of N-sulfonylpiperidine-3-carboxamide derivatives as capsid assembly modulators inhibiting HBV in vitro and in HBV-transgenic mice.

Yin J, Feng Z, Li Z, Hu J, Hu Y, Cai X, Zhou H, Wang K, Tang N, Huang A, Huang L. Yin J, et al. Among authors: huang l, huang a. Eur J Med Chem. 2023 Mar 5;249:115141. doi: 10.1016/j.ejmech.2023.115141. Epub 2023 Jan 23. Eur J Med Chem. 2023. PMID: 36709646

5

PLEKHG5 is stabilized by HDAC2-related deacetylation and confers sorafenib resistance in hepatocellular carcinoma.

Sha Y, Pan M, Chen Y, Qiao L, Zhou H, Liu D, Zhang W, Wang K, Huang L, Tang N, Qiu J, Huang A, Xia J. Sha Y, et al. Among authors: huang l, huang a. Cell Death Discov. 2023 May 29;9(1):176. doi: 10.1038/s41420-023-01469-z. Cell Death Discov. 2023. PMID: 37248230 Free PMC article.

6

High dietary fructose promotes hepatocellular carcinoma progression by enhancing O-GlcNAcylation via microbiota-derived acetate.

Zhou P, Chang WY, Gong DA, Xia J, Chen W, Huang LY, Liu R, Liu Y, Chen C, Wang K, Tang N, Huang AL. Zhou P, et al. Cell Metab. 2023 Nov 7;35(11):1961-1975.e6. doi: 10.1016/j.cmet.2023.09.009. Epub 2023 Oct 4. Cell Metab. 2023. PMID: 37797623 Free article.

7

PCK1 attenuates tumor stemness via activating the Hippo signaling pathway in hepatocellular carcinoma.

Liu R, Liu Y, Zhang W, Zhang G, Zhang Z, Huang L, Tang N, Wang K. Liu R, et al. Among authors: huang l. Genes Dis. 2023 Sep 16;11(4):101114. doi: 10.1016/j.gendis.2023.101114. eCollection 2024 Jul. Genes Dis. 2023. PMID: 38560500 Free PMC article.

8

Identification of a diketopiperazine-based O-GlcNAc transferase inhibitor sensitizing hepatocellular carcinoma to CDK9 inhibition.

Shan X, Jiang R, Gou D, Xiang J, Zhou P, Xia J, Wang K, Huang A, Tang N, Huang L. Shan X, et al. Among authors: huang l, huang a. FEBS J. 2023 Sep;290(18):4543-4561. doi: 10.1111/febs.16877. Epub 2023 Jun 5. FEBS J. 2023. PMID: 37247228 Free article.

9

O-GlcNAcylation of E3 ubiquitin ligase SKP2 promotes hepatocellular carcinoma proliferation.

Feng Z, Yin J, Zhang Z, Chen Z, Huang L, Tang N, Wang K. Feng Z, et al. Among authors: huang l. Oncogene. 2024 Apr;43(15):1149-1159. doi: 10.1038/s41388-024-02977-7. Epub 2024 Feb 23. Oncogene. 2024. PMID: 38396292

10

O-GlcNAcylation of SPOP promotes carcinogenesis in hepatocellular carcinoma.

Zhou P, Chang WY, Gong DA, Huang LY, Liu R, Liu Y, Xia J, Wang K, Tang N, Huang AL. Zhou P, et al. Oncogene. 2023 Mar;42(10):725-736. doi: 10.1038/s41388-022-02589-z. Epub 2023 Jan 5. Oncogene. 2023. PMID: 36604567

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