Okkenhaug K - Search Results

1

Acquisition of suppressive function by conventional T cells limits antitumor immunity upon T_reg depletion.

Whiteside SK, Grant FM, Alvisi G, Clarke J, Tang L, Imianowski CJ, Zhang B, Evans AC, Wesolowski AJ, Conti AG, Yang J, Lauder SN, Clement M, Humphreys IR, Dooley J, Burton O, Liston A, Alloisio M, Voulaz E, Langhorne J, Okkenhaug K, Lugli E, Roychoudhuri R. Whiteside SK, et al. Among authors: okkenhaug k. Sci Immunol. 2023 Dec 15;8(90):eabo5558. doi: 10.1126/sciimmunol.abo5558. Epub 2023 Dec 15. Sci Immunol. 2023. PMID: 38100544 Free PMC article.

2

Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer.

Ali K, Soond DR, Pineiro R, Hagemann T, Pearce W, Lim EL, Bouabe H, Scudamore CL, Hancox T, Maecker H, Friedman L, Turner M, Okkenhaug K, Vanhaesebroeck B. Ali K, et al. Among authors: okkenhaug k. Nature. 2014 Jun 19;510(7505):407-411. doi: 10.1038/nature13444. Epub 2014 Jun 11. Nature. 2014. PMID: 24919154 Free PMC article.

3

Blockade of phosphatidylinositol 3-kinase PI3Kδ or PI3Kγ reduces IL-17 and ameliorates imiquimod-induced psoriasis-like dermatitis.

Roller A, Perino A, Dapavo P, Soro E, Okkenhaug K, Hirsch E, Ji H. Roller A, et al. Among authors: okkenhaug k. J Immunol. 2012 Nov 1;189(9):4612-20. doi: 10.4049/jimmunol.1103173. Epub 2012 Sep 28. J Immunol. 2012. PMID: 23024273

4

A point mutation in CD28 distinguishes proliferative signals from survival signals.

Okkenhaug K, Wu L, Garza KM, La Rose J, Khoo W, Odermatt B, Mak TW, Ohashi PS, Rottapel R. Okkenhaug K, et al. Nat Immunol. 2001 Apr;2(4):325-32. doi: 10.1038/86327. Nat Immunol. 2001. PMID: 11276203

5

Corrigendum: Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer.

Ali K, Soond DR, Piñeiro R, Hagemann T, Pearce W, Lim EL, Bouabe H, Scudamore CL, Hancox T, Maecker H, Friedman L, Turner M, Okkenhaug K, Vanhaesebroeck B. Ali K, et al. Among authors: okkenhaug k. Nature. 2016 Jul 28;535(7613):580. doi: 10.1038/nature17641. Epub 2016 Apr 6. Nature. 2016. PMID: 27049952 No abstract available.

6

Key role of the p110delta isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110delta function in B cells.

Bilancio A, Okkenhaug K, Camps M, Emery JL, Ruckle T, Rommel C, Vanhaesebroeck B. Bilancio A, et al. Among authors: okkenhaug k. Blood. 2006 Jan 15;107(2):642-50. doi: 10.1182/blood-2005-07-3041. Epub 2005 Sep 22. Blood. 2006. PMID: 16179367 Free article.

7

PI3K p110δ is expressed by gp38(-)CD31(+) and gp38(+)CD31(+) spleen stromal cells and regulates their CCL19, CCL21, and LTβR mRNA levels.

Zotes TM, Spada R, Mulens V, Pérez-Yagüe S, Sorzano CO, Okkenhaug K, Carrera AC, Barber DF. Zotes TM, et al. Among authors: okkenhaug k. PLoS One. 2013 Aug 29;8(8):e72960. doi: 10.1371/journal.pone.0072960. eCollection 2013. PLoS One. 2013. PMID: 24009720 Free PMC article.

8

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice.

Selman C, Lingard S, Choudhury AI, Batterham RL, Claret M, Clements M, Ramadani F, Okkenhaug K, Schuster E, Blanc E, Piper MD, Al-Qassab H, Speakman JR, Carmignac D, Robinson IC, Thornton JM, Gems D, Partridge L, Withers DJ. Selman C, et al. Among authors: okkenhaug k. FASEB J. 2008 Mar;22(3):807-18. doi: 10.1096/fj.07-9261com. Epub 2007 Oct 10. FASEB J. 2008. PMID: 17928362

9

Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde traffic.

Stewart H, Palmulli R, Johansen KH, McGovern N, Shehata OM, Carnell GW, Jackson HK, Lee JS, Brown JC, Burgoyne T, Heeney JL, Okkenhaug K, Firth AE, Peden AA, Edgar JR. Stewart H, et al. Among authors: okkenhaug k. bioRxiv [Preprint]. 2022 Dec 22:2021.01.06.425396. doi: 10.1101/2021.01.06.425396. bioRxiv. 2022. Update in: EMBO Rep. 2023 Dec 6;24(12):e57224. doi: 10.15252/embr.202357224 PMID: 33442692 Free PMC article. Updated. Preprint.

10

Author Correction: PI3K inhibitors are finally coming of age.

Vanhaesebroeck B, Perry MWD, Brown JR, André F, Okkenhaug K. Vanhaesebroeck B, et al. Among authors: okkenhaug k. Nat Rev Drug Discov. 2021 Oct;20(10):798. doi: 10.1038/s41573-021-00300-7. Nat Rev Drug Discov. 2021. PMID: 34471263 No abstract available.

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