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Acquisition of suppressive function by conventional T cells limits antitumor immunity upon Treg depletion.
Whiteside SK, Grant FM, Alvisi G, Clarke J, Tang L, Imianowski CJ, Zhang B, Evans AC, Wesolowski AJ, Conti AG, Yang J, Lauder SN, Clement M, Humphreys IR, Dooley J, Burton O, Liston A, Alloisio M, Voulaz E, Langhorne J, Okkenhaug K, Lugli E, Roychoudhuri R. Whiteside SK, et al. Among authors: humphreys ir. Sci Immunol. 2023 Dec 15;8(90):eabo5558. doi: 10.1126/sciimmunol.abo5558. Epub 2023 Dec 15. Sci Immunol. 2023. PMID: 38100544 Free PMC article.
Interferon lambda is required for interferon gamma-expressing NK cell responses but does not afford antiviral protection during acute and persistent murine cytomegalovirus infection.
Gimeno Brias S, Marsden M, Forbester J, Clement M, Brandt C, Harcourt K, Kane L, Chapman L, Clare S, Humphreys IR. Gimeno Brias S, et al. Among authors: humphreys ir. PLoS One. 2018 May 16;13(5):e0197596. doi: 10.1371/journal.pone.0197596. eCollection 2018. PLoS One. 2018. PMID: 29768502 Free PMC article.
IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine.
McLaren JE, Clement M, Marsden M, Miners KL, Llewellyn-Lacey S, Grant EJ, Rubina A, Gimeno Brias S, Gostick E, Stacey MA, Orr SJ, Stanton RJ, Ladell K, Price DA, Humphreys IR. McLaren JE, et al. Among authors: humphreys ir. J Immunol. 2019 Feb 1;202(3):943-955. doi: 10.4049/jimmunol.1701757. J Immunol. 2019. PMID: 30635396 Free PMC article.
The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors.
Thompson A, Davies LC, Liao CT, da Fonseca DM, Griffiths JS, Andrews R, Jones AV, Clement M, Brown GD, Humphreys IR, Taylor PR, Orr SJ. Thompson A, et al. Among authors: humphreys ir. PLoS Pathog. 2019 Jun 26;15(6):e1007850. doi: 10.1371/journal.ppat.1007850. eCollection 2019 Jun. PLoS Pathog. 2019. PMID: 31242262 Free PMC article.
83 results