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Page 1
Role of platelet count in a murine stasis model of deep vein thrombosis.
Mathews R, Setthavongsack N, Le-Cook A, Kaempf A, Loftis JM, Woltjer RL, Lorentz CU, Revenko A, Hinds MT, Nguyen KP. Mathews R, et al. Among authors: lorentz cu. Platelets. 2024 Dec;35(1):2290916. doi: 10.1080/09537104.2023.2290916. Epub 2023 Dec 15. Platelets. 2024. PMID: 38099327 Free article.
Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial.
Lorentz CU, Verbout NG, Wallisch M, Hagen MW, Shatzel JJ, Olson SR, Puy C, Hinds MT, McCarty OJT, Gailani D, Gruber A, Tucker EI. Lorentz CU, et al. Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):799-809. doi: 10.1161/ATVBAHA.118.312328. Arterioscler Thromb Vasc Biol. 2019. PMID: 30700130 Free PMC article. Clinical Trial.
The protein C activator AB002 rapidly interrupts thrombus development in baboons.
Tucker EI, Verbout NG, Markway BD, Wallisch M, Lorentz CU, Hinds MT, Shatzel JJ, Pelc LA, Wood DC, McCarty OJT, Di Cera E, Gruber A. Tucker EI, et al. Among authors: lorentz cu. Blood. 2020 Feb 27;135(9):689-699. doi: 10.1182/blood.2019002771. Blood. 2020. PMID: 31977000 Free PMC article. Clinical Trial.
Antibody inhibition of contact factor XII reduces platelet deposition in a model of extracorporeal membrane oxygenator perfusion in nonhuman primates.
Wallisch M, Lorentz CU, Lakshmanan HHS, Johnson J, Carris MR, Puy C, Gailani D, Hinds MT, McCarty OJT, Gruber A, Tucker EI. Wallisch M, et al. Among authors: lorentz cu. Res Pract Thromb Haemost. 2020 Feb 11;4(2):205-216. doi: 10.1002/rth2.12309. eCollection 2020 Feb. Res Pract Thromb Haemost. 2020. PMID: 32110750 Free PMC article.
Pharmacological targeting of coagulation factor XI mitigates the development of experimental atherosclerosis in low-density lipoprotein receptor-deficient mice.
Ngo ATP, Jordan KR, Mueller PA, Hagen MW, Reitsma SE, Puy C, Revenko AS, Lorentz CU, Tucker EI, Cheng Q, Hinds MT, Fazio S, Monia BP, Gailani D, Gruber A, Tavori H, McCarty OJT. Ngo ATP, et al. Among authors: lorentz cu. J Thromb Haemost. 2021 Apr;19(4):1001-1017. doi: 10.1111/jth.15236. Epub 2021 Feb 10. J Thromb Haemost. 2021. PMID: 33421301 Free PMC article.
Pharmacological reduction of coagulation factor XI reduces macrophage accumulation and accelerates deep vein thrombosis resolution in a mouse model of venous thrombosis.
Jordan KR, Wyatt CR, Fallon ME, Woltjer R, Neuwelt EA, Cheng Q, Gailani D, Lorentz C, Tucker EI, McCarty OJT, Hinds MT, Nguyen KP. Jordan KR, et al. J Thromb Haemost. 2022 Sep;20(9):2035-2045. doi: 10.1111/jth.15777. Epub 2022 Jul 18. J Thromb Haemost. 2022. PMID: 35638310 Free PMC article.
28 results