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PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease.
Hsu WJ, Wildburger NC, Haidacher SJ, Nenov MN, Folorunso O, Singh AK, Chesson BC, Franklin WF, Cortez I, Sadygov RG, Dineley KT, Rudra JS, Taglialatela G, Lichti CF, Denner L, Laezza F. Hsu WJ, et al. Among authors: singh ak. Exp Neurol. 2017 Sep;295:1-17. doi: 10.1016/j.expneurol.2017.05.005. Epub 2017 May 15. Exp Neurol. 2017. PMID: 28522250 Free PMC article.
Environmental Enrichment and Social Isolation Mediate Neuroplasticity of Medium Spiny Neurons through the GSK3 Pathway.
Scala F, Nenov MN, Crofton EJ, Singh AK, Folorunso O, Zhang Y, Chesson BC, Wildburger NC, James TF, Alshammari MA, Alshammari TK, Elfrink H, Grassi C, Kasper JM, Smith AE, Hommel JD, Lichti CF, Rudra JS, D'Ascenzo M, Green TA, Laezza F. Scala F, et al. Among authors: singh ak. Cell Rep. 2018 Apr 10;23(2):555-567. doi: 10.1016/j.celrep.2018.03.062. Cell Rep. 2018. PMID: 29642012 Free PMC article.
Identification of peptidomimetics as novel chemical probes modulating fibroblast growth factor 14 (FGF14) and voltage-gated sodium channel 1.6 (Nav1.6) protein-protein interactions.
Liu Z, Wadsworth P, Singh AK, Chen H, Wang P, Folorunso O, Scaduto P, Ali SR, Laezza F, Zhou J. Liu Z, et al. Among authors: singh ak. Bioorg Med Chem Lett. 2019 Feb 1;29(3):413-419. doi: 10.1016/j.bmcl.2018.12.031. Epub 2018 Dec 15. Bioorg Med Chem Lett. 2019. PMID: 30587448 Free PMC article.
JAK2 regulates Nav1.6 channel function via FGF14Y158 phosphorylation.
Wadsworth PA, Singh AK, Nguyen N, Dvorak NM, Tapia CM, Russell WK, Stephan C, Laezza F. Wadsworth PA, et al. Among authors: singh ak. Biochim Biophys Acta Mol Cell Res. 2020 Oct;1867(10):118786. doi: 10.1016/j.bbamcr.2020.118786. Epub 2020 Jun 26. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 32599005 Free PMC article.
5,915 results